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Biomedical subjects

A H Swerdlin

Publications and source records attributed to A H Swerdlin.

7 recordsLinked to original sources
PubMed1980

Hypernatremia in hepatic failure.

The presence of hypernatremia in patients with hepatic failure has not received major attention. We examined the records of 25 patients admitted to the hospital with decompensated liver disease (usually Laënnec's cirrhosis) and found hypernatremia in 15. Probable causes include increased insensible water losses, impairment of water intake due to encephalopathy, and the use of osmotic cathartics with hypotonic enteric losses. Patients in this series showing hypernatremia had a mortality of 87%. Mortality in those without hypernatremia was 60%. The presence of increased serum sodium concentrations in patients with decompensated liver disease is an ominous but correctable abnormality reflecting a disturbance in water balance.

Adult↗
PubMed1980

Hepatic coma after open heart surgery.

Fulminant hepatic failure has been reported in patients with chronic congestive heart failure. Two patients in whom jaundice and coma followed cardiac surgery were studied to find the possible etiology. Clinical, biochemical, and histologic evaluations revealed low cardiac output; elevated levels of bilirubin, lactic dehydrogenase, serum glutamic oxaloacetic transaminase, and alkaline phosphatase; prolonged prothrombin time; and centrizonal necrosis of hepatocytes with sinusoidal dilatation. No other possible causes of hapatic dysfunction and coma were identified. We conclude that acute postoperative congestive heart failure may cause fulminant hepatic failure and metabolic encephalopathy.

Acute Disease↗
PubMed1980

Mesangial proliferative glomerulonephritis in mixed connective tissue disease (MCTD).

A patient who had clinical and serologic evidence for Mixed Connective Tissue Disease (MCTD) developed mesangial proliferative glomerulonephritis with demonstrable immune complexes. Most cases of MCTD with a renal lesion have exhibited membranous glomerular lesions. Since the prevalence of renal involvement in MCTD has ranged from 5-20%, it is possible that too few cases have been studied to describe fully the range of renal lesions seen in this disease entity.

Adult↗
PubMed1978

Hazards of computerized tomography: renal failure following contrast injection.

Acute renal failure in a diabetic patient following contrast injection for computerized tomography is discussed. Like a variety of serious complications associated with contrast media, dye-induced renal failure is an important iatrogenic complication to which the diabetic population may be unusually susceptible.

Acute Kidney Injury↗