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Biomedical subjects

A Hallak

Publications and source records attributed to A Hallak.

45 records · Page 3Linked to original sources
PubMed1983

Blastogenic response of lymphocytes derived from patients with hematopoietic malignancies to antigens of a type C retrovirus isolated from a Burkitt's lymphoma cell line.

Cellular immune response to antigens associated with a type C retrovirus derived from Burkitt's lymphoma (BL) lymphoblastoid cells was studied in patients with hematopoietic malignancies, noncancer patients and healthy controls. Response was determined by lymphocyte blastogenesis assay measuring [3H]-thymidine incorporation, thereby enabling the calculation of stimulation indices (SI). Positive response (SI greater than 2.0) was demonstrated in patients with multiple myeloma (MM), chronic lymphocytic leukemia (CLL), chronic myelocytic leukemia (CML) and BL. No response was demonstrated in the non-cancer and healthy controls. Specific blastogenic response was obtained towards antigen extracted from three different cell lines infected with the tested type C retrovirus. No response was evident towards purified whole or purified disrupted virions or antigen extracted from murine myeloma MOPC-315 cells secreting a murine type C retrovirus or an antigen extracted from Mason-Pfizer monkey virus-infected NC-37 cells. The correlation between human hematopoietic malignancies and the in vitro lymphocyte blastogenic response to the BL-derived type C retrovirus was statistically highly significant.

Adult↗
PubMed1983

Endoscopic removal of a giant duodenal polyp.

A 50-year-old female with a giant duodenal polyp is described. An uneventful endoscopic removal of the polyp was performed. An aggressive endoscopic approach to such tumors seems to be justified regardless of their size.

Adenoma↗
PubMed1982

Malabsorption syndrome, coccidiosis, combined immune deficiency, and fulminant lymphoproliferative disease.

Coccidia were found in a patient suffering from malabsorption syndrome. In addition, immunologic investigation showed combined humoral and cellular immunodeficiency. Treatment with metronidazole induced the disappearance of coccidia from the stool and clinical remission. Six months later, the patient was seen with acute lymphoproliferative disease and died thereafter. The possible relationship between malabsorption, immunodeficiency, coccidiosis, metronidazole, and malignancy is reviewed.

Adult↗
PubMed1980

Consumption of refined carbohydrate by patients with Crohn's disease in Tel-Aviv-Yafo.

In 27 patients with Crohn's disease living in Israel the current intake of refined carbohydrate (total sugars) and added sugar is significantly greater than in healthy controls. The dietary survey was retrospective and showed that patients with Crohn's disease ate 269 g of monosaccharides and disaccharides each day compared with 192 g by matched controls. Similar differences were also found at the onset of the symptoms, 314 g compared with 207 g. These findings were independent of the country of origin or cultural grouping. Several factors are discussed which suggest a secondary rather than causal relationship between sugar consumption and Crohn's disease.

Crohn Disease↗
PubMedDate not supplied

Supernumerary nostrils: a case report and review.

Supernumerary or accessory nostrils are a very rare type of congenital nasal anomaly, with only a few cases reported in the literature. They can be associated with such malformations as facial clefts and they can be unilateral or bilateral, with most cases reported being unilateral. The accessory nostril may or may not communicate with the ipsilateral nasal cavity, probably depending on the degree of embryological progression of the anomaly. A case of simple supernumerary left nostril with no nasal cavity communication and with a normally developed nose is presented. The surgical treatment is described and the different speculative theories related to the embryogenesis of supernumerary nostrils are also reviewed.

Female↗