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Biomedical subjects

A Hammer

Publications and source records attributed to A Hammer.

68 records · Page 4Linked to original sources
PubMed1981

Trampoline training injuries--one hundred and ninety-five cases.

In 198 people 201 trampoline injuries are analysed. All except three adults were re-examined, following an observation period of one to four years. School children (145) represented the major part of the 195 persons re-examined. Handling the large trampoline injured 21 of the 145 school children and six children at clubs. Injuries of a permanent nature were found in 49 of the 195 who were re-examined. The biomechanics and physiology of trampoline jumping is evaluated. Mismatch of a multitude of sensory impulses (visual, tactile, others) with impulses from the vestibular apparatus converging towards the orientation centres of the brain, may result in disorientation and then in the inadequate motor reactions actually seen at the time of the trampoline accidents. A G-induced split second loss of consciousness is another possible explanation of the trampoline accident. More secure procedures than trampolining as a school-sport and recreational activity are recommended.

Adolescent↗
PubMed1978

Patellar fracture after replacement of the tibio-femoral joint with the ICLH prosthesis.

Four cases are reported of spontaneous fracture of the patella after ICLH replacement of the knee for Rheumatoid Arthritis. Three of these occur-red in patellae that had not themselves been replaced; one in a resurfaced patella. The former required no specific treatment but the latter required revision surgery. It is argued that the existence of this complication may represent a contra-indication to patellar replacement in the osteoporotic rheumatoid knee.

Arthritis, Rheumatoid↗
PubMedDate not supplied

Selective cholesteryl ester uptake from high density lipoprotein by human first trimester and term villous trophoblast cells.

As villous trophoblast does represent the contact zone between foetal and maternal tissues, the present in vitro study was aimed at investigating cholesterol supply from human high density lipoprotein subclass 3 (HDL(3)) to trophoblast cells isolated from human first trimester and term placenta. Binding of (125)I-HDL(3) was specific and saturable with similar K(d)-values for first trimester (54 microg HDL(3)-protein/ml) and term villous trophoblast cells (29 microg HDL(3)-protein/ml). The cell-association of (125)I-HDL(3) was 3-fold higher for term trophoblast cells while the specific cell-association of [(3)H]cholesterol ester(CE)-labelled HDL(3) was higher for first trimester trophoblast preparations. As a consequence, first trimester trophoblast cells have a pronounced capacity for selective CE-uptake from HDL(3). Competition experiments with native and oxidized low-density lipoprotein as well as cAMP-mediated stimulation of cell-association of [(3)H]CE-HDL(3) in both trophoblast preparations suggested the scavenger receptor class B, type I (SR-BI) as a likely receptor mediating this pathway. SR-BI m RNA could be identified by RT-PCR and Northern blot experiments in both trophoblast preparations. Western blot analysis and immunocytochemistry revealed high expression of SR-BI in first trimester trophoblast. A polyclonal antiserum raised against murine SR-BI significantly decreased cell-association of [(3)H]CE-HDL(3) in trophoblast cells. We conclude that human first trimester and term trophoblast cells express SR-BI which could serve as an efficient route for supplying cholesterol esters from maternal lipoproteins to foetal tissues.

Adult↗
PubMedDate not supplied

Salivary gland neoplasia in the dog and cat: survival times and prognostic factors.

Twenty-four dogs and 30 cats with histopathologically confirmed salivary gland neoplasia were retrospectively reviewed in a multi-institutional study. The predominant presenting complaint for animals with salivary gland neoplasia was that of a mass being noted by the owner; other common complaints included halitosis, dysphagia, and exophthalmia. Siamese cats were overrepresented, indicating a possible breed predisposition. The most common histopathological type was simple adenocarcinoma. Cats had more advanced disease at diagnosis than did dogs, and clinical staging was prognostic in dogs. The median survival times for dogs and cats were 550 days and 516 days, respectively.

Adenocarcinoma↗