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Biomedical subjects

A Hanukoglu

Publications and source records attributed to A Hanukoglu.

54 records · Page 3Linked to original sources
PubMed1986

Inheritance of familial primary endocardial fibroelastosis.

Two related families with 15 children, seven of whom developed endocardial fibroelastosis (EFE) are described. Three of the children died during infancy, and the disease was confirmed in one of them at autopsy. The survivors, two sisters age 5 years and 15 months (Family A) and two sisters age 17 and 14 years (Family B), are now symptomless and show a decrease in left ventricular hypertrophy. The mode of inheritance of EFE in our two families appears to be either autosomal or X-linked dominant with reduced penetrance.

Carnitine↗
PubMed1984

Benign paroxysmal torticollis in infancy.

We present four children with benign paroxysmal torticollis (BPT) and a review of the literature. BPT appears to be a self-limited disorder that occurs predominantly in females. The attacks of head tilting usually start in infancy, may recur at varying intervals until the age of 1 to 5 years, and may be confused with other seizures. Other symptoms, such as ataxia and vomiting, may be associated with the attacks of torticollis. Less frequently, infantile migraine also may be associated.

Ataxia↗
PubMed1983

Muscle involvement in Schönlein-Henoch syndrome.

Three patients with Schönlein-Henoch syndrome developed severe muscle pain in the legs. The pain, so severe that they were bedridden, subsided within a few days and was caused, we believe, by bleeding into the leg muscles.

Child↗
PubMed1982

The differential leukocyte count in shigellosis.

We analysed the peripheral leukocyte count of 80 children with shigella gastroenteritis. The total leukocyte count varied widely from leukopenia to leukocytosis, and is therefore of little value in differentiating shigellosis from viral gastroenteritis. The leukocyte differential count, however, revealed a striking shift to the left in 71% of the patients. This parameter may help in the preliminary diagnosis of shigella gastroenteritis. We have stressed the fact that three pediatric textbooks do not refer to this aspect in their relevant chapters on shigellosis.

Child↗
PubMed1982

Leukocyte transfusion in severe neonatal varicella.

A female neonate with severe varicella is reported. She was treated with THF and a leukocyte transfusion from her convalescent mother. This procedure seems to have been a turning point, after which she recovered fully. There were no untoward effects from this treatment.

Blood Transfusion↗
PubMed1980

Dyphenylhydantoin induced hypersensitivity reaction with an unusual purpuric skin lesion.

We describe a boy with an unusual adverse reaction to dyphenylhydantoin (DH). This 12 years old boy developed a clinical picture of high fever, scarlatiniform rash, a hemorrhagic (purpuric) skin lesion, on his buttocks and neck, stomatitis and conjunctivitis, within two weeks after DH administration. Laboratory examinations were compatible with the diagnosis of disseminated intravascular coagulation. Cases similar to ours are reviewed and it is stressed that DH should be used cautiously as it is not a harmless drug.

Child↗
PubMed1979

Torsion of the spleen in a five-and-a-half-month-old infant.

In this report, we describe torsion of the spleen in a five-and-a-half-month-old infant, thus far the youngest reported patient in the literature. Celiac angiography and tuftsin determination confirmed the clinical impression that the pathology was confined to the spleen. The infant underwent a splenectomy and made an uneventful recovery.

Celiac Artery↗
PubMedDate not supplied

Lung abscess caused by Streptococcus pneumoniae type 3. The importance of counterimmunoelectrophoresis in laboratory diagnosis.

We are reporting the case of an 18-month-old girl with a post-pneumonic lung abscess. The counterimmunoelectrophoresis (CIE) of the patient's urine during the bacteremic phase of the disease gave a precipitation line with pneumococcal antiserum. Later in the course of the disease, after the diagnosis of lung abscess had been established, the pus drained from the abscess gave positive reactions with pneumococcal omnivalent serum and type 3 pneumococcal antiserum. At this stage, the pus was sterile and blood cultures were negative. This case demonstrates that the CIE test is a simple procedure which gives a rapid and exact diagnosis up to the serotype level.

Counterimmunoelectrophoresis↗
PubMedDate not supplied

Pulmonary involvement in Mycoplasma pneumoniae infection in families.

The transmission rate and the clinical and pulmonary manifestations of serologically proven mycoplasma infections were reviewed in 34 patients from 11 families consisting of 30 children and adolescents aged 1 to 18 years, and four parents aged 30 to 41 years (total number of family members = 59:37 children, 22 adults). Twenty-seven of the 37 children had pulmonary involvement (73%). The total infection rate was 58%, and the infection rate in children 81%. The roentgenologic findings in children with pneumonia showed no pathognomonic features. The most common X-ray finding was bronchopneumonia (48%). Pulmonary infiltrates occurred in six children (20%) under four years of age. Three of the children (10%) had severe clinical and/or radiological manifestations. These findings depict a pattern of mycoplasma infection that is different from previous reports, i.e. high pulmonary infection rates in families, the occurrence of pneumonic infiltrations in young children and a quite severe clinical and radiological course in some of the patients.

Adolescent↗