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Biomedical subjects

A Hartai

Publications and source records attributed to A Hartai.

At least 19 recordsLinked to original sources
PubMed1982

Simultaneous occurrence of hyperkalemia due to aldosterone suppression and hyperfunctioning parathyroid adenoma.

The change of the pattern of clinical presentation of primary hyperparathyroidism in older patients is illustrated by a case history of a 61-year-old woman with multicystic kidney disease in whom a thiazide antihypertensive drug (clopamide) induced a very severe symptomatic hypercalcemia. Withdrawal of the drug was followed by a prolonged complete clinical remission, normocalcemia, normocalciuria, but consistently elevated parathormone levels. This "normocalcemic biochemical hyperparathyroidism" was complicated with hyperkalemia due to aldosterone suppression, a counterpart of the recently described association with hypokalemia due to primary hyperaldosteronism, necessitating further studies on the occurrence and significance of altered production of aldosterone in geriatric patients with primary hyperparathyroidism.

Acid-Base Equilibrium↗
PubMed1982

Comparison of azosemide and furosemide in ascitic patients without and during administration of spironolactone.

Clinical, pharmacodynamic, and renal effects of a new diuretic, azosemide, were studied and compared with those of furosemide. Graded single intravenous (100-1600 mg) or peroral (100-400 mg) doses were administered to six patients with ascites due to liver cirrhosis without and during basic treatment with spironolactone. A standard peroral dose (160 mg) of both diuretics was found to have similar effectiveness. There was no difference in the time-course of action as determined on the basis of 24-h urine volume, sodium excretion, and osmolal clearance in four patients during basic treatment with spironolactone. However, azosemide appeared to be more effective than furosemide in those patients in whom a dose-response curve was established. Unlike furosemide, azosemide was much more effective when given intravenously than orally. Our study confirmed that azosemide is a "loop diuretic" with renal sites of action similar to those of furosemide. However, it has a higher efficiency, probably due to the steeper dose-response relationship.

Administration, Oral↗
PubMed1981

Influence of posture on serum potassium changes during standard glucose tolerance test.

Serum potassium (SK) decreased in a significantly greater extent (p less than 0.005) in the recumbent (0.91 +/- 0.11 mmol/L) than in the upright position (0.57 +/- 0.07 mmol/L) in the course of the standard glucose tolerance test (StGTT) in 12 normal people. The clinical implications with special respect to "paradoxical hyperkalemia" are discussed.

Glucose Tolerance Test↗