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Biomedical subjects

A Hashizume

Publications and source records attributed to A Hashizume.

30 records · Page 2Linked to original sources
PubMed1987

Wet dog shakes in limbic versus generalized seizures.

Wet dog shake behavior was studied in different models of epilepsy in the rat. Numerous wet dog shakes were associated with limbic seizures in the course of focal epilepsy induced by kindling stimulations or local injections of kainic or quisqualic acid and progressively disappeared during generalization. On the contrary, they were never observed in models of generalized epilepsy. This study suggests that the number of wet dog shakes may be an index of the progression of limbic seizures toward generalization.

Amygdala↗
PubMed1987

Unilateral exophthalmos caused by an invasive pituitary adenoma.

A case of pituitary adenoma associated with unilateral exophthalmos is reported. An intraorbital infiltrative tumor growth was verified by histopathological study. The mechanism of exophthalmos is discussed, and edema of the intraorbital tissue secondary to an inflammatory reaction or venous stasis associated with tumor cell infiltration is considered to be the cause of exophthalmos in this patient.

Adenoma, Chromophobe↗
PubMed1984

[Pituitary oncocytoma].

Since the first reports of pituitary oncocytoma by Kovacs and Horvath, and Landolt and Oswald increasing numbers of cases have been reported with the advent of electron microscopy. It has been posturated that more cases were not precisely diagnosed because of lack of electron microscopic study. We reported two cases of pituitary oncocytoma and discussed clinicopathological aspects. Case 1 A 66-year-old woman had a 6 year history of visual impairment. Neurological examination revealed loss of vision on the left and decreased visual acuity (0.3) with temporal hemianopsia on the right. The endocrinological study revealed moderate panhypopituitarism. Plain skull X-ray, computed tomography and cerebral angiography showed the findings of a pituitary tumor with suprasellar extension. Subfrontal removal of the tumor followed by irradiation was performed. Case 2 A 50-year-old man was well until 8 years previously, when he experienced loss of libido. Three years before entry, the left sided exophthalmos and ptosis were noted. Neurological examination showed a severe visual impairment with a bitemporal field defect, bilateral optic atrophy and disturbance of eye movements on the left. Endocrinological study revealed panhypopituitarism. Radiological studies showed a pituitary tumor with a suprasellar extension and an invasion into the left orbital cavity. Transcranial and then transsphenoidal partial removal of the tumor were done followed by irradiation. Histological examination of the tumors revealed a poorly granurated adenoma with very weak affinity to acid dyes.(ABSTRACT TRUNCATED AT 250 WORDS)

Adenoma↗
PubMed1983

[Wet-dog shaking behavior in rats in hippocampal kindling].

The kindling phenomenon, induced by repetitive electrical stimulation of the hippocampus of the rat is associated with the production of a particular behavior: the Wet Dog Shakes (WDS). The evolution of WDS is strongly and negatively correlated with the intensification of motor seizures. Some differences can be seen in the occurrence of WDS according to whether the stimulation is applied in dorsal or in ventral hippocampus. Although the anatomical substrate responsible for this behavior is not clearly defined, the relationship between WDS and kindling let us consider it as an index of the generalization of the epilepsy.

Animals↗
PubMed1982

Short latency somatosensory evoked spinal and scalp-recorded potentials following posterior tibial nerve stimulation in man.

Short latency somatosensory evoked potentials (SEPs) following posterior tibial nerve stimulation at the ankle were studied by using surface electrodes placed on the spine and scalp with a non-cephalic reference (unipolar recording) in normal young adults. In order to improve recording technique, ECG was used to trigger the stimulator, and bilateral simultaneous stimulation was employed. A triphasic (positive-negative-positive) or biphasic (negative-positive) potential was recorded at each spinal electrode. Latency of this potential was longer in the more rostral channels. Conduction velocity of the spinal cord from the 12th thoracic to the 2nd cervical spine was 73.4 +/- 7.53 m/sec. At scalp electrodes, 4 components (P25, N27, P28 and N31) were identified preceding the major positive peak (P36). These 4 components showed similar latency and amplitude at all 4 electrodes investigated (Fs, Fz, C3 and C4) and are considered to be generated in the deep structure. Especially, P25 is estimated to be generated in the ascending sensory pathway of the upper cervical cord, but generator sources of other components remain to be determined. P36 appears to be generated in the somatosensory foot area.

Adult↗