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Biomedical subjects

A Hatwal

Publications and source records attributed to A Hatwal.

5 recordsLinked to original sources
PubMed1989

Association of hypomagnesemia with diabetic retinopathy.

Serum magnesium was measured in 100 patients of type II diabetes mellitus (40 without retinopathy, 40 with non-proliferative and 20 with proliferative retinopathy) without malnutrition, hepatic or renal disease or albuminuria and in 100 age and sex matched controls. The serum magnesium levels were lower in diabetics than in controls (P less than 0.001), and the levels in diabetics with non-proliferative and proliferative retinopathy were significantly lower than in those without retinopathy (P less than 0.001). These data seem to point towards an association between hypomagnesemia and diabetic retinopathy.

Aged↗
PubMed1989

Oral clonidine: an effective growth hormone provocative test.

Twenty normal statured healthy children (8 M; 12 F) aged 9-16 years were subjected to growth hormone (GH) provocative tests. The mean basal GH level was 2.0 +/- 0.42 ng/ml (+/- SEM). The mean peak levels of GH were 11.9 +/- 2.19 ng/ml (+/- SEM) after exercise, 9.82 +/- 2.81 ng/ml (+/- SEM) after insulin and 15.2 +/- 2.54 ng/ml (+/- SEM) after oral clonidine. A significant rise (peak level greater than 7 ng/ml) of serum GH was found in 70, 80 and 85% of children after exercise, insulin and oral clonidine tests, respectively. The observation in the present study indicates that oral clonidine test, a safer, easier and more economical test than insulin hypoglycemia, is equally potent and can be done in out patients.

Administration, Oral↗
PubMed1988

Spironolactone and cimetidine in treatment of acne.

In an open therapeutic trial, 50 patients with acne vulgaris were randomly allocated to one of two groups. One group received spironolactone 100 mg daily and the other cimetidine 1.6 g daily for 12 weeks. Clinical severity of acne and sebum excretion decreased significantly at the end of the trial with both drugs, but significantly more with spironolactone. Mean serum levels of testosterone, androstenedione and dehydroepiandrosterone-sulfate decreased significantly with spironolactone but showed no change with cimetidine. Our data suggest that spironolactone may be useful as antiandrogen in the short term therapy of acne vulgaris.

Acne Vulgaris↗