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A Heikkinen

Publications and source records attributed to A Heikkinen.

21 records · Page 2Linked to original sources

Transitional cell tumours of the urinary bladder. The histological grade (WHO) and the clinical stage (UICC).

Correlation of histological grade (WHO) with clinical stage (UICC) of transitional epithelial tumours of the bladder has been evaluated in 130 patients. A moderate statistically highly significant positive correlation was established (Pearson's r 0.37--0.75 and eta correlation ratio coefficient 0.49--0.81 in various subsets of the material). Transurethral biopsies gave on average 0.53 lower histological grade than open operative biopsies of the same tumours. The data show that the information contained in histological grade and clinical stage is parallel and support the idea that histological diagnosis of transitional cell carcinoma is possible also in the absence of histological evidence of invasion.

Aged↗

Tissue antibodies in malignant and benign urogenital disease.

The presence of anti-tissue antibodies in sera from patients with genitourinary carcinomas and non-malignant genitourinary diseases was studied by indirect immunofluorescence. An increased incidence of various tissue antibodies was observed in carcinomas of the urinary bladder, prostate and kidney when compared to controls. There was a trend towards association between antinuclear antibodies and metastatic undifferentiated tumors. A low degree of malignancy was associated with antibodies against connective tissue "reticulin". A striking similarity between tissue antibody "patterns" in carcinoma patients and patients with chronic renal inflammation was seen. This points to inflammation as being an important factor in tissue antibody production.

Adult↗