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A Hetherington

Publications and source records attributed to A Hetherington.

3 recordsLinked to original sources

Failure of transcutaneous electrical stimulation to alleviate experimental tourniquet pain.

It has been proposed that transcutaneous electrical nerve stimulation (TENS) acts by stimulation of large nerve fibers which inhibits further propagation of nociceptive input conducted along smaller C-nerve fibers. We evaluated the effectiveness of TENS in alleviation of ischemic pain (C-fiber mediated) experimentally produced by the submaximal-effort tourniquet test. Cutaneous electrodes were placed proximal to the tourniquet and TENS was begun prior to exsanguination of the arm. Time from inflation of the tourniquet to onset of intolerable pain was noted together with a visual analog-derived intensity of pain for 10 subjects studied on three separate occasions. The results showed no statistically significant prolongation in the duration of ischemia tolerated nor reduction in the subjective intensity of pain during either single- or dual-channel stimulation in comparison to control levels.

Adult

Contact allergic sensitivity to chrysanthemum and the photosensitivity dermatitis and actinic reticuloid syndrome.

Of sixty-nine examples of the photosensitivity dermatitis and actinic reticuloid syndrome, nine were found to be allergically sensitive to chrysanthemum oleoresin extract. Although this extract showed evidence in vitro of a phototoxic action we were unable with in vivo studies to explain the connection between the contact allergic sensitivity and the photosensitivity. The fractions responsible for the in vitro phototoxicity appear to be different from those involved in the in vivo contact allergic sensitivity. This study provides further support for the view that in the photosensitivity dermatitis and actinic reticuloid syndrome contact allergic sensitivity is of importance.

Aged