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Biomedical subjects

A Hipp

Publications and source records attributed to A Hipp.

6 recordsLinked to original sources

[Obesity--an interdisciplinary task].

In industrial nations, over the last five decades conditions concerning nutrition and physical exercise as well as socio-economic circumstances have changed radically. One of the consequences following from this development has been a rapid increase in the prevalence of obesity. Studies have shown that currently 20 percent of the German adult population suffer from obesity. Investigations into the etiology of obesity have to address complex interactions between genetic, socio-economic and psychosocial factors. A year ago, at the University Hospital Tübingen different departments joined to set up the "Plattform Adipositas". Endocrinologists, obesity surgeons, professionals in sports medicine and psychosomatic medicine as well as dieticians are collaborating to develop scientifically based therapy programs and treatment pathways for obese patients. The following article gives an account of this exemplary interdisciplinary cooperation.

Germany↗

[Lactate in cardiac rehabilitation].

BACKGROUND: Training increases work capacity and concomitantly quality of life, and also, according to new data, the life expectancy of patients with coronary heart disease and heart failure. At the same time, the importance of adequate training intensity increases aiming at low complications and high efficacy. ASSESSMENT OF EXERCISE CAPACITY: The objective of the present work is to define objective training guidance parameters in cardiac rehabilitation. Maximal exercise capacity must be distinguished from the performance without symptoms of oxygen deficit. The latter used to be early surpassed in untreated stabile angina pectoris. Within the last decade optimized therapy often yields a cardiac performance limit above the anaerobic threshold derived from lactate measurements. The concepts of aerobic and anaerobic thresholds derived from the lactate performance curve are introduced and modified leaving the 4 mmol/l lactate threshold concept to meet the criteria for performance capacity and breaking point in cardiac patients. The relationship to threshold concepts derived from spirometric data is mentioned as well as from stress hormones. The heart rate at the anaerobic threshold measured at treadmill ergometry systematically lies above the one from bicycle ergometry. Lactate increases faster with advancing age and the anaerobic threshold is earlier reached and progressively so because of the reduced muscle mass and reduced endurance capacity of people of the industrialized countries. IMPORTANCE: The determination of the anaerobic threshold as an objective criteria independent of motivation leads to training control, as shown by an example. Ineffective training above the threshold giving rise to catecholamines can be avoided by lactate performance diagnostic. Additionally, the success of rehabilitation measures can objectively be quantified and documented much better from the threshold work capacity than from maximal exercise tolerance. Preliminary reports indicate the importance of lactate diagnostics for rehabilitation guidance in heart failure.

Adult↗

The echocardiographic determination of volume and muscle mass of the heart.

One- and two-dimensional echocardiography permits assessment of left ventricular size and muscle mass, whereas the validity and reliability differ. It is comparable to other methods, such as angiography, scintigraphy and magnetic resonance imaging, but has the advantage of being noninvasive and of lower cost. It therefore appears particularly well-suited for applications in sports medicine. However, changes of 10%-20%, depending on the parameter, are necessary in individual cases to permit assumption of a proven change. A further methodical improvement, especially in respect to reliability but also to validity may be expected in the future from three-dimensional, computer-supported examination techniques. Enlargement of the heart due to endurance sports is harmonic and affects all four cardiac chambers. Limits to the increase in left ventricular volume and muscle mass can be recognized in relation to body weight. They usually do not exceed 70% of the baseline value or the value obtained for untrained persons. Power training, even in extreme forms, results in no or only minimal dimensional changes.

Adaptation, Physiological↗

Echocardiographic findings in endurance athletes with hypertrophic non-obstructive cardiomyopathy (HNCM) compared to non-athletes with HNCM and to physiological hypertrophy (athlete's heart).

Hypertrophic non-obstructive cardiomyopathy (HNCM) is one of the most frequent causes of sudden cardiac death in young athletes. Since the clinical findings in HNCM patients may be inconspicuous and the ECG changes found in endurance athletes may be similar to those of HNCM patients, echocardiography, as a non-invasive procedure, seems to take on an important role in differential diagnostics. To prove this hypothesis, conventional echocardiographic parameters were compared in three groups with confirmed diagnosis: Group I: HNCM (n = 9) without sports activity; Group II: HNCM (n = 9) with regular, intensive endurance training (3-5 hours/week). The diagnosis was invasively confirmed in both groups. Group III: healthy subjects (n = 9) with physiological hypertrophy and regular endurance training (3-6 hours/week). In the presence of HNCM, endurance sports activity appears to offset the reduction in the left ventricle and enlargement of the left atrium. The wall thickness of the septum and posterior wall do not differ in the two HNCM groups, but show a significant difference to the healthy athletes. The enddiastolic diameter, the absolute septum and posterior wall thickness and the ratio of septum+posterior wall/enddiastolic diameter can be taken as the most important differential diagnostic criterium in physiological hypertrophy, but not the ratio between septum/posterior wall. It is concluded that conventional echocardiographic examination can be considered a valuable non-invasive method for differentiating HNCM from athlete's heart, even in patients with HNCM who participate in endurance sports. However, a reliable diagnosis may not be possible in individual cases.

Adolescent↗