In-utero fetal therapy with immunoglobulin for alloimmune thrombocytopenia.
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Biomedical subjects
Publications and source records attributed to A Huch.
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By a study of the patterns of changes and the temporal relationship in fetal heart rate, intrauterine pressure, fetal tcPO2 and 'flow', a series of ten typical examples of combined patterns are described. Fetal tcPO2 is affected by the level of the fetal oxygenation and by the blood flow beneath the electrode. Should the latter be below a certain critical level fetal tcPO2 will be lower than fetal scalp blood PO2. By the integrated analysis of the four simultaneously recorded variables the different factors dominating fetal tcPO2 may be identified.
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In summary we would like to state that the correlation between tcPO2 recorded from human fetal scalp and microblood PO2 is quite good. High tcPO2 values are very reassuring for the clinician and indicate a good oxygenation of the fetus. In the presence of a low tcPO2 reading, other signs of fetal hypoxia like abnormal heart rate patterns or a low microblood PO2 are required to confirm the diagnosis. If a low tcPO2 is the only sign suggestive of fetal hypoxia and all other parameters are normal, we recommend removal of the electrode and reapplication in a different spot.
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