PubMed Health⌕ Search

Biomedical subjects

A Hullo

Publications and source records attributed to A Hullo.

At least 19 recordsLinked to original sources
PubMed2006

A questionnaire survey on the management of Graves' orbitopathy in Europe.

OBJECTIVE: To determine management patterns among clinicians who treat patients with Graves' orbitopathy (GO) in Europe. DESIGN AND METHODS: Questionnaire survey including a case scenario of members of professional organisations representing endocrinologists, ophthalmologists and nuclear medicine physicians. RESULTS: A multidisciplinary approach to manage GO was valued by 96.3% of responders, although 31.5% did not participate or refer to a multidisciplinary team and 21.5% of patients with GO treated by responders were not managed in a multidisciplinary setting. Access to surgery for sight-threatening GO was available only within weeks or months according to 59.5% of responders. Reluctance to refer urgently to an ophthalmologist was noted by 32.7% of responders despite the presence of suspected optic neuropathy. The use of steroids was not influenced by the age of the patient, but fewer responders chose to use steroids in a diabetic patient (72.1 vs 90.5%, P<0.001). Development of cushingoid features resulted in a reduction in steroid use (90.5 vs 36.5%, P<0.001) and increase in the use of orbital irradiation (from 23.8% to 40.4%, P<0.05) and surgical decompression (from 20.9 to 52.9%, P<0.001). More ophthalmologists chose surgical decompression for patients with threatened vision due to optic neuropathy, who were intolerant to steroids than other specialists (70.3 vs 41.8%, P<0.01). CONCLUSION: Deficiencies in the management of patients with GO in Europe were identified by this survey. Further training of clinicians, easier access of patients to specialist multidisciplinary centres and the publication of practice guidelines may help improve the management of this condition in Europe.

Decompression, Surgical↗
PubMed1999

[Primary ocular lymphoma manifesting as anterior uveitis. Apropos of a case].

We report the case of a primitive ocular lymphoma occurring in a 48 year old patient. Non-Hodgkin's lymphomas are usually found in ocular localizations, and are often associated with a lymphomatous cerebral affection. The most frequent mode of presentation of these rare intra ocular tumors is usually posterior uveitis with chorioretinal lesions, and must be suspected for every long-standing chronic uveitis, especially posterior ones. The diagnosis can only be based on histological or cytological analysis. Our patient presented a primary ocular lymphoma which was initially revealed by an anterior uveitis and had evolved into a panuveitis that was resistant to treatment. The initial checkup of this uveitis remained negative and did not allow for an etiological diagnosis. The eye came less operational, hypertonic crisis became more frequent and controlled less and less by the treatment, therefore the patient had to be enucleated in order to establish a diagnosis and for therapeutic reasons. The histology revealed the existence of a NK lymphoma.

Chronic Disease↗
PubMed1998

Case-control study of the risk factors for age related macular degeneration. France-DMLA Study Group.

AIM: A case-control study was initiated to determine the risk factors for the development of age related macular degeneration (AMD). METHODS: Study participants, who were all white, aged 50-85 years, and were recruited from private ophthalmology practices. Each practitioner enrolled patients with bilateral AMD, who were then matched with controls for sex and age. Environmental factors and systemic and ocular histories were screened. All patients had bilateral red-free fundus photographs and fluorescein angiography. Photographs were classified into pigment epithelium alterations, drusen, geographic atrophy, and exudative AMD. Statistical analysis included the identification of risk factors for AMD. A multivariate analysis was performed at the end of the study. Analysis included the entire study population and was carried out for each stage of AMD. RESULTS: 1844 controls were compared with 1844 patients with AMD. Mean age was 71 years for controls and 72 for cases. Logistic regression identified six major risk factors for AMD (whole population): arterial hypertension (odds ratio (OR) = 1.28), coronary disease (OR = 1.31), hyperopia (OR = 1.33), light coloured irises (OR = 1.22), and lens opacities or previous cataract surgery (OR = 1.55). The significance of vascular risk factors was increased for late stages of AMD, especially the atrophic forms (coronary disease, OR = 3.19). CONCLUSIONS: This large case-control study confirms some of the risk factors previously identified and may contribute to the determination of methods for prevention of AMD.

Age Distribution↗
PubMed1997

[Late effects of radiation on the eye and ocular adnexa].

Late ocular effects after irradiation of the eyes and ocular adnexa are reviewed. Ocular and orbital injuries occur more often after irradiation of central nervous system neoplasms or treatment of paranasal sinus malignancies. The complete loss of vision is the major complication which is multifactorial. This paper describes the radiation effects and grading of ocular adnexa, lens, retina, optic nerves and orbit. The tolerance doses and treatment are described.

Dose-Response Relationship, Radiation↗
PubMed1992

[Acanthamoeba keratitis. Morphologic and isoenzymatic study of a strain isolated from a medically treated case].

We report here the third case of Acanthamoeba keratitis discovered in France in a 30 year-old man wearing soft contact lenses. Amoebas of Acanthamoeba genus could be isolated twice from his corneal ulcer with simple ocular swabs. Owing to medical treatment alone, a successful healing of his eye was obtained. The isolated strain was studied morphologically and biochemically: the cysts observed microscopically after silver stain possessed less than six arms surrounded by a non reticulated ectocyst and belonged to group II defined by Pussard and Pons. But the isoenzymatic study of the ocular strain by isofocusing did not allow us to identify it with any one of the 18 reference strains used, although these represent 14 different described species.

Acanthamoeba↗
PubMed1989

[Measurement of visual acuity in infants in 6 minutes: Teller's Acuity Cards].

Most of the development of infant visual function occurs during the first year of life. Early pathological symptoms affecting visual or oculomotor processes, particularly ocular misalignment or amblyopia, should be detected and treated at the earliest age. Orthoptic and ophthalmological tests have been available for a long time but there remained a need for a convenient test for measuring visual acuity. Preferential looking techniques fulfill this demand and have been proven reliable and convenient to estimate visual acuity in preverbal infants. A new commercial presentation of the test, called Teller Acuity Cards, is described. Testing an infant was rapid, 5 to 6 minutes for a normal child, and easy because the child enjoys the convivality of the situation. Space requirement is reduced. Measures were taken from a population of 50 normal children aged 4 to 12 months. All children responded in the three situations, binocular and monocular (there was no blind eye in the group). Grating acuity values were higher than those obtained by projection preferential looking techniques. Binocular acuity was 6.5 cycles/deg (approximately 2.5/10) at 4 months of age, 9.8 cycles/deg (approximately 3.3/10) at 9 months and up to 13 cycles/deg (approximately 5/10) around 12 months. Acuities were found to be half an octave lower in monocular condition as compared to binocular. Orthoptic and ophthalmological check-up of infants is important, especially in case of children at risk of visual disorder. In most instances acuity can be preserved by therapeutic action provided it is initiated during the first year of life, when sensitivity to appropriate stimulation is at its peak.(ABSTRACT TRUNCATED AT 250 WORDS)

Humans↗
PubMed1989

[Detection of vision disorders in newborn infants and children].

Early detection of visual deficits is of most importance in childhood. To be adequately treated; it requires systematic screening before 18 months of age. Basic tests include objective refraction study (skiascopy), preferential sight test with estimation of visual acuity which is possible after 3 months of age, and, if poor vision, is found, electroretinography evoked visual potentials is performed. Many disorders can be recognized early on and treated (mainly strabismus, congenital cataract or glaucoma). The early correction of refractive disorders results in good visual development and subsequent facility in reading and writing.

Child↗
PubMed1988

[Early evaluation of the vision of infants: baby vision, a reality today].

Non invasive techniques such as preferential looking, Teller acuity cards and orthoptic examination allow an early detection and treatment of visual defect. As early as 3 months of age, the pediatrician should refer to an ophthalmologist any child at risk on the ground of its personal or family history. Visual evoked potentials and retinography should be used in the case of more severe problems.

Electronystagmography↗
PubMed1987

[Examination of convergent strabismus in children].

Esotropia or converging squint is a common pathology in early age, generally followed by unilateral functional amblyopia of the deviating eye if an adapted treatment is not prescribed very early. Amblyopia occurs when the subject has lost use of one eye, now constantly deviating. Every strabismic child must have an early complete ophthalmologic examination. The author describes the main steps of this examination and discusses the diagnostic aspects. The main differential diagnosis is benign pseudo-strabismus of the epicanthus.

Child↗
PubMed1987

[Convergent strabismus in children. Clinical aspects and treatment].

The classification of convergent strabismus of the child, "esotropies", is mainly based upon the age of appearance. It is indeed fundamental to distinguish the early esotropies where the recovery of binocular vision is impossible and the orthoptic reeducation unnecessary, from the late forms where orthoptic reeducation and treatment could achieve the recovery of the binocular vision.

Child, Preschool↗