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Biomedical subjects

A Hurse

Publications and source records attributed to A Hurse.

5 recordsLinked to original sources
PubMed1981

Methicillin-resistant Staphylococcus aureus bacteraemia.

Twenty-eight (53%) of 53 hospital-acquired staphylococcal bacteraemias which occurred at The Royal Melbourne Hospital over a two-year period were due to methicillin-resistant Staphylococcus aureus (MRSA). Every patient with MRSA bacteraemia had a significant underlying condition predisposing to nosocomial sepsis, and each had an intravascular foreign body in situ at the time. Most were being nursed in special care areas of the hospital and had been exposed to multiple or broad-spectrum antibiotics during the month before development of bacteraemia. Patients acquiring MRSA infection should be isolated and, when the diagnosis of bacteraemia is considered, any potential primary focus should be removed. Vancomycin is the drug of choice in life-threatening MRSA infections.

Catheterization↗
PubMed1981

In-vitro activity of erythromycin against anaerobic microorganisms.

Minimum inhibitory concentrations of erythromycin were determined, in the absence of CO2, for 256 strains of anaerobic microorganisms recently isolated from clinical practice. Of 126 strains of Bacteroides fragilis, 93% were inhibited by 6 mg/L, or less, of erythromycin. Of the remaining 130 isolates, 92% were inhibited by 6 mg/L, or less, of erythromycin. These findings suggest that the majority of anaerobic microorganisms would be inhibited by the serum levels achieved by administering 1 g of erythromycin intravenously, every six hours.

Bacteria↗
PubMedDate not supplied

The emergence of gentamicin-resistant klebsiellae in a large general hospital.

Between March and December, 1975, an outbreak of infection with gentamicin-resistant Klebsiella pneumoniae (klebsiella (Gmr)) occurred at the Royal Melbourne Hospital. The klebsiellae were considered to be causing significant infection in 24 of 42 patients harbouring the microorganism. Commonest culture sources were urine and sputum, all but one of the significant urinary infections being associated with indwelling bladder catheters. Antibiotic therapy had been given to 40 patients before the isolation of klebsiella (Gmr), and of these 22 had received gentamicin. Cross infection was a major factor in the outbreak, and control measures (to limit this aspect and curtail the usage of gentamicin) have prevented wider spread within the hospital; at the time of writing the microorganism had been eradicated from all but one of the infected patients. It was shown that klebsiella (Gmr) carry an R-factor capable of transferring gentamicin resistance. Of 22 isolates tested quantitatively, 20 were resistant to 10 mug/ml of gentamicin.

Australia↗