[Differential diagnosis of acute gastrointestinal hemorrhage with a tumoral etiology].
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Biomedical subjects
Publications and source records attributed to A I Gorbashko.
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The authors describe an original variant of gastric resection which was performed in 65 patients with ulcer of the cardial portion of the stomach with good immediate and remote results.
Technical peculiarities of a new method of gastric resection are described. Mobilization of the portion being removed was performed without an injury of main vessels and nerves. The secondary branches running to the part being resected should be subjected to parietal ligation or dissection. Operations were made on 52 patients for gastric ulcer or polyps. Immediate and remote results were good.
The authors observed 353 patients with acute gastro-intestinal hemorrhages of tumorous etiology. It was shown that modern methods of diagnosis could reveal the correct cause and localization of the source of hemorrhage in 97.5% of patients and objectively estimate the degree of blood loss. The individual methods of treatment enabled the general lethality to be reduced to 29.8% and after radical operations to 7.5%.
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Experience with the treatment of 224 patients with acute ileus is described. Direct correlation has been established between outcomes of the treatment and terms of staying at the hospital and surgery. Due to late consultation with a physician and diagnostic errors 29% of patients were admitted to the hospital later than in a day. The causes of errors, risk and complications are analyzed. Ways for their prevention are proposed. Lethality after the surgical treatment of acute ileus was 9.3%.
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The main characteristics of systemic hemodynamics and relative changes in the blood content, blood flow and uptake of intravenous 86Rb in several tens of organs, tissues and parts of the body were examined in rat experiments 6 days after ligation of the common bile duct. This made it possible to appraise the resistive, capacitance and capillary constituents of the general peripheral vascular resistance. In this case the fractions of cardiac discharge diminished in a number of the internal organs of the abdomen and increased in muscle and bone tissues of the chest. The signs of extensive venodilation were defined, with these signs being the least remarkable in the liver and lungs. Transcapillary permeability for 86Rb substantially increased in the organs of the splanchic area and in the lungs.
The relationship between the disorders in the indices of the internal medium of the organism and the volume of blood loss, the number of recurrent hemorrhages, the length of the posthemorrhagic period was established on the basis of experimental, laboratory, instrumental investigations and the experience of treatment of 1987 patients with acute gastro-intestinal hemorrhages. The advantages of active methods and the early urgent operation over other kinds of treatment were supported by the immediate results of operations in 415 patients with profuse gastro-intestinal hemorrhage of ulcerous etiology. The terms and results of operations were shown to be in direct dependence. The mortality rate after the operations performed within 24 hours was 1%.
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Variations in the structure of vagus nerves studied in 264 organocomplexes of corpses were compared with the data obtained during operations on 122 patients subjected to different modifications of vagotomy. The use of the obtained anatomotopographic picture of the gastric vessels and nerves permitted preserving not only the organ operated upon but also provided the completely undisturbed innervation and blood supply of the stomach and adjacent organs. The results of examination of 176 patients subjected to proximal selective vagotomy and transverse resection of the stomach with the preserved pyloric constrictor showed that at most preserved vascularization and innervation permit to avoid incompetent sutures of anastomosis, its stenosis, dumping syndrome, gastric atonia and diskinesia of biliary ducts.
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The data on 130 patients with acute ulcers of the gastrointestinal tract complicated hemorrhage and perforation are reported. Acute ulcers developed in patients with cardiovascular diseases (47%), intoxication (17.7%), postoperative paresis of the stomach and intestine (10%), other pathology (15.3%), and in medication (10%). The former manifested in acute hemorrhage in 108 patients, perforation--in 8, hemorrhage and perforation--in 14. In 86% of cases ulcers were located in the stomach, and in 63%--these were multiple. Conservative therapy was employed in 97 patients and 33 patients were operated upon. The mortality after early operations was 2.5 times as low as in the expectation policy and conservative therapy.
On the grounds of experimental and topographo-anatomic findings and surgical experience with 62 patients the authors present the indications for and technic of transverse resection of the stomach with the preservation of the pyloric constrictor. Three modifications of this operation developed by the authors are described. These modifications were used for the treatment of peptic and duodenal ulcer, polyposis and benign tumor of the stomach. The peculiarities and nerves, maximal vascularization and innervation of the pyloric constrictor, natural passage of the food from the stomach.
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