[Ultrastructure of erythroid series cells in experimental lead poisoning].
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Biomedical subjects
Publications and source records attributed to A I Gracheva.
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In rabbits exposed to lead poisoning electron microscopy revealed the presence in reticulocytes and erythrocytes of differently sized vacuoles, an amassment of ferritin granules in the mitochondria along with autophaging vacuoles; leucocytes evidenced turgescence of the mitochondria, up to and including their destruction and emptiness; the blood platelets showed an abundant vacuolization with disordered distribution of the serotonin and glycogen granules. The above changes become most spectacular on the 7-21st day after poisoning and by the 50th day they are encountered but in isolated cells.