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Biomedical subjects

A I Kravchenko

Publications and source records attributed to A I Kravchenko.

At least 19 recordsLinked to original sources
PubMed2001

[ECG based diagnosis of right ventricular hypertrophy in patients with chronic obstructive bronchitis].

Two mathematical models developed on the basis of a discriminant analysis of the evidence obtained in examination of 84 patients with chronic obstructive bronchitis (COB) are proposed in early diagnosis of right ventricular hypertrophy (RVH) by ECG readings in COB patients. Application of hierarchic classification model is recommended for diagnosis of RVH in screening. The probability model is intended for follow-up of COB patients.

Aged↗
PubMed1997

[Alexithymia in personal characteristics of patients with coronary heart diseases].

Psychological status was assessed in 120 patients with coronary heart disease (CHD) according to MMPI, Toronto alexithymic scale. Alexithymia was diagnosed in 49.1% of the examinees. They were characterized by difficulties in definition of their feelings, absence of dreams and fantasies, introversion, inclination to depressive response to stress, hypochondria eventuating in senesthopathy. The above psychological and pathopsychological traits in CHD patients require psychotherapeutic and chemotherapeutic correction in order to enhance efficacy of the treatment.

Adult↗
PubMed1992

[The effect of synthetic enkephalins on prostaglandin synthesis and lipid peroxidation in the isolated heart during the activation of free-radical processes].

The system Fe(2+)-ascorbate was used for lipid peroxidation (LPO) activation in isolated heart tissue. The stimulation of free radical processes in the myocardium caused a rise in the level of LPO products and a significant lowering of that of prostacyclin. Intravenous injection of synthetic analogues of enkephalins before LPO activation inhibited LPO and resulted in prostacyclin synthesis normalization. The addition of peptides under study into perfusion solution led to a decrease in LPO primary products level and in thromboxane synthesis.

Animals↗
PubMed1975

[The effect of 11-deoxycortiocosterone acetate on the antitumor activity of prospidin].

Male rats with sarcoma 45 being intact with respect to the adrenal gland and thyroid were subjected to bilateral adrenalectomy or thyroidectomy. The experiments have indicated that 11-desoxycorticosterone acetate (DOCA) injected intramuscularly in the dosage of 30-45 and 80-90 mg/Kg daily during 6-8 days (terms of observation-14-16 days since the moment of tumor transplantation) lessens the antiblastic effect of prospidine (injected intraperitoneally in the same dosage and regimen), especially in an impaired mineral metabolism, caused by adrenalectomy. The growth of sarcoma 45 was found to be retarded in bilateral adrenalectomy or thyroidectomy in rats. Epinephrectomized animals showed the entire absence of this effect in DOCA injection. In thyroidectomized and adrenalectomized animals the antiblastic effect of prospidine was more pronounced than in intact (with respect to the thyroid and adrenal gland) rats.

Adrenalectomy↗