Biomedical subjects
Publications and source records attributed to A I Krupatkin.
The peculiarities of craniovertebral abnormalities and dysplasias in children and adolescents have been studied. Different diagnostic methods (dopplerography of spinal arteries, ultrasonography, remote infrared thermography, laser doppler flowmetry, etc) were compared. The outlines for treatment the patients with cervical dysplasias are described.
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Neurotrophic effects on tissues microcirculation in upper limbs traumas were revealed by 9-year investigations using electroneuromyography, capillaroscopy of the nail matrix, polarography, oxygen test, hydrogen clearance test. It is shown that oxygen polarography is most adequate for evaluation of nerve trophism. A total of 136 patients with neuropathies of 174 nerves have been examined. Of principal importance for the results interpretation is examination of the neurosecretory function of thin nonmyelinated fibers and vasoactive neuropeptides in neuromicrocirculatory interactions. The action potential of neurotrophic substances depends on their tissue levels.
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Squeezed syndrome affecting various segments of limbs has been identified in 245 of 500 victims randomized for examination 6 months after the earthquake. In 119 cases associated with closed fractures of long tubular bones and in 59 cases with open ones. In 124 cases duration of squeezing was up to 12 h, and in 70 cases--1 day and more. Segmental limb amputation was performed in 113 cases. In 95 cases limbs functions were retained and in 81--lost. Perspectives of more successful outcomes depend on the maximal shortening of rescue period, on rational organization of the treatment process and prolongation of recovery management of squeezed syndrome sequelae.
The article is devoted to the investigation of actual at present problem of incongruent pain in patients with spine osteochondrosis. 26 patients with congruent and 24 patients with incongruent pain, intensity and localization of which did not correspond to organic disturbances, have been examined. The results of comparison of two groups demonstrated involvement of central mechanisms, namely physiologic, in the pain syndrome formation in patients with incongruent pain. They demonstrate the necessity of differentiated approach in the treatment of the patients of the mentioned group, including psychotherapeutic measures.
The authors analyze the remote results of treatment of 56 patients with neglected injuries to the median and/or ulnar nerves after combined surgical interventions including restoration of the nerves, flexor tendons, one of the main arteries, and correction of neurogenic deformation of the hand. The results were assessed according to a specially developed comprehensive scheme with due consideration for recovery of individual structures of the hand and of its total function. Good and satisfactory results were achieved in 96 percent of patients, which fact recommends combined surgical interventions for the treatment of neglected injuries to the hand and finger nerves.
As the result of examination of 43 patients with injury to the ulna neurovascular bundle the author studied the regeneration of the ulnar nerve in and without reconstruction of the ulnar artery. The outcomes of ulnar nerve autoplasty are better in restoration of the artery than in application of an epineural suture. Sensitivity and tissue trophies increase essentially, the strength of the hand muscles increases to a lesser degree. Reconstruction of the ulnar artery has the best effect on regeneration of the nerve injured on the forearm and above its ramification on the palm. An important factor is early increase of blood supply and oxygenation, which promotes trophics of the graft, and perfusion of the intergrowiny axons and the surrounding tissues.
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