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Biomedical subjects

A I Lopotko

Publications and source records attributed to A I Lopotko.

At least 19 recordsLinked to original sources
PubMed2002

Protective effect of calcium channel blocker verapamil on morphological and functional state of hair cells of the organ of corti in experimental kanamycin-induced ototoxicity.

The protective effect of verapamil against acute ototoxic sensorineural damage produced by intraperitoneal injections of kanamycin (50 mg/kg daily for 14 day) was studied on rats. The functional (otoacoustic emission), histological, and physiological methods proved the protective effect of daily injections of calcium channel blocker verapamil (2 mg/kg) on the state of hair cells of the organ of Corti.

Animals↗
PubMedDate not supplied

[Device for measuring the acoustic impedance of the middle ear].

There exists a direct proportional relation between the acoustic impedance of the tympanic membrane and static pressure in the external acoustic duct. This relation forms the basis of the UM-01 device which enables the acoustic impedance to be determined and allows it to judge from its magnitude on the condition of the sound-conducting sector of the auditory analyser. The device is simple to handle and does not require any balancing of the measuring portion in the circuit.

Acoustics↗
PubMedDate not supplied

[Problems of diagnosis and treatment of atypical mastoiditis].

The specific features of the diagnosis and therapy of the dry form of atypical mastoiditis are discussed. Of great diagnostic importance were local changes in the mastoid area, otoscopic signs in the posterior-superior tympanic membrane and bone compartment of the auditory meatus, hearing impairment, thermographic signs of purulent-destructive lesions in the antrum and other cells of the mastoid process, and X-ray symptoms of bone destruction of the mastoid process. It is obvious that the clinical picture and development of atypical mastoiditis are closely related to the age and reactivity of the patient, irrational use of antibiotics and physiotherapy, concomitant diseases, especially endocrine pathologies.

Acute Disease↗