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Biomedical subjects

A I Ruderman

Publications and source records attributed to A I Ruderman.

At least 19 recordsLinked to original sources
PubMed1988

[Late results of treating cervical cancer with a proton beam].

The authors described methods of cervical cancer therapy performed in 1970 using the proton beam of the Institute of Theoretical and Experimental Physics and analyzed long-term results. The use of protons resulted in homogeneous irradiation of a preset target volume without injuring the adjacent organs and tissues. Proton beam irradiation of the uterus was combined with gamma-beam therapy of the zones of regional metastatic spreading. Postradiation reactions were unobserved in the adjacent bladder and rectum in patients receiving combined therapy and irradiation alone. The clinical efficacy of proton beam irradiation was confirmed by the treatment of 160 patients.

Combined Modality Therapy↗
PubMed1987

[6-unit clinico-physical complex].

The article is devoted to the results of application of high energy proton beams, negative pi-mesons and neutrons in biomedical and clinical investigations carried out at the 680 MeV phasotron (the JINR Laboratory of Nuclear Problems) before its conversion. A six-compartment clinico-physical facility is described. It has been constructed at the converted phasotron in order to continue and expand investigations for application of heavy nuclear particles in radiation therapy. The first physical and dosimetric characteristics of medical proton beams produced in the converted accelerator and guided to chambers 1 and 2 of the new clinico-physical facility are discussed. The future of radiobiological and clinical investigations with high energy proton, negative pion and neutron beams of this facility is also discussed.

Facility Design and Construction↗
PubMed1983

[Prospects for using the Institute of Theoretical and Experimental Physics proton beam for treating gynecologic cancer patients].

Untoward side-effects of exposure of normal tissues surrounding tumor in the course of radiation treatment were avoided due to the use of a proton beam developed at the Institute of Theoretical and Experimental Physics. As a result, no post-treatment complications were observed in the surrounding tissues of the urinary bladder and rectum in 175 cancer patients (tumors of the vulva-39 and cervix uteri-136) who received a course of complex radiation treatment and preoperative irradiation.

Aged↗