PubMed Health⌕ Search

Biomedical subjects

A I Shugaev

Publications and source records attributed to A I Shugaev.

At least 19 recordsLinked to original sources
PubMed1987

[Experimental substantiation of intestinal sorption in acute pancreatitis].

Enterosorption on the carbon material Vaulen was performed in experiments in albino rats with the model of acute pancreatitis. The application of enterosorbents was shown to increase the percentage of survival of the animals, to decrease the activity of pancrease enzymes in the blood, components of the Kallikrein-Kinin system, proteolysis products. The clinical observations support the expediency of using this detoxication method.

Acute Disease↗
PubMed1987

[Hemosorption in the treatment of endogenous toxemia in acute pancreatitis].

One of important components of endogenous intoxication in acute pancreatitis is considered to be middle-mass molecules possessing high toxicity. Hemosorption improves results of complex therapy and reduces postoperative lethality by 10% at an average. The positive effect of hemosorption in focal pancreanecrosis is associated with sorption of lipase, trypsin, middle-mass molecules and other metabolites. In total pancreanecroses the effect of hemosorption was minimal. In hemosorption on the sorbent SKN the oxygenation and regional heparinization of the sorbent is indicated.

Acute Disease↗
PubMed1986

[Acute cholecystitis and liver failure].

The article presents results of treatment of 300 patients with acute cholecystitis, 285 of them (95%) being operated upon. Hepatic insufficiency was found to develop in 173 patients (57,6%). The operation of choice was cholecystectomy (97,1%). Cholecystostomy was fulfilled in 7 patients (2,4%), in 2 patients (0,5%) choledocholithotomy was made following a previous cholecystectomy. Lethality in patients with hepatic insufficiency was 4 times as high as in patients without it. In 34,1% of the operated patients hepatic insufficiency was the main cause of death.

Acute Disease↗
PubMed1986

[Cholelithiasis and hepatic insufficiency].

During the recent years 202 patients with cholelithic disease and its complications have been treated in the clinic. In 135 patients admitted to the hospital an attack of severe pains was followed by jaundice and symptoms of hepatic insufficiency (HI). A compensated stage of HI was diagnosed in 68 (50.4%) patients, subcompensated stage--in 38 (28.1%), decompensated--in 25 (18.5%) and terminal stage of HI--in 4 patients (3%). The operative treatment was used in 142 patients (70.3%). The operation of choice was cholecystectomy. An intervention on the common bile duct was performed in 59 patients (41.5%). Operations were performed on 42 patients with the compensated stage of HI (one of them died), in 17 patients with the subcompensated stage (one patient died), in 16 patients with the decompensated stage (three patients died); with the terminal stage there were 4 patients operated upon. Two of them died.

Adult↗
PubMed1980

[Therapeutic procedure in relation to kidney failure in acute pancreatitis].

The article is concerned with the role of proteolytic enzymes of the pancreas in the development of renal insufficiency in acute pancreatitis. In 70 patients the activity of tripsin, tripsin inhibitor in the blood were assessed as well as the function of kidneys and morphological alterations in them. The authors propose a scheme of etiopathogenesis of renal insufficiency in acute pancreatitis, the greatest significance being attached to disorders in the systematic and renal hemodyanmics, immunizing inflammation of the connective tissue of the kidneys by the products of pancreas autolysis.

Acute Disease↗