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A I Spriggs

Publications and source records attributed to A I Spriggs.

At least 37 records · Page 2Linked to original sources
PubMed1978

Joint fluid cytology in Reiter's disease.

The diagnostic value of the finding of cytophagocytic macrophages (CPM) in the joint fluid of patients with Reiter's disease has been re-examined. CPM were found in 46% of Reiter's disease fluids and in 45% of other inflammatory knee joint fluids. Higher CPM scores, on a 4-point grading, were commoner in Reiter's disease but the difference was not statistically significant. Further, although the graded polymorphonuclear leucocyte phagocytosis shown by CPM was greater in Reiter's disease this also was not significant. It is concluded that the presence of CPM in joint fluid is of little discriminating value.

Arthritis, Reactive↗
PubMed1977

Cervical smears.

Explore the source record for details and available documents.

Adolescent↗
PubMed1976

Adenocarcinoma of the uterine cervix: cytological evidence of a long preclinical evolution.

Adenocarcinoma of the cervix occurred in 13 women who had previously had "negative" cervical smears. These smears were reviewed, and abnormalities were found in six cases, the intervals ranging from two to eight years. It is concluded that adenocarcinoma, like squamous carcinoma of the cervix, can have a prolonged evolution during which it is cytologically detectable.

Adenocarcinoma↗
PubMed1976

Duplication of part of the long arm of chromosome 1 in marrow cells of a treated case of myelomatosis.

In a case of classical myelomatosis treated with melphalan, a clone of cells with a chromosomal abnormality was found in the bone marrow during remission. There was good reason to think that the hemopoietic cells, rather than plasmacytoma cells, were implicated. Although the clone persisted, no evidence of leukemia developed over a period of observation of 2 yr. The anomaly was interpreted as a duplication of part of the long arm of chromosome 1, which appeared to involve the segment q21 to q31.

Aged↗
PubMed1975

Intracellular mucous inclusions. A feature of malignant cells in effusions in the serous cavities, particularly due to carcinoma of the breast.

Three cases of carcinoma of the breast are described, in which similar tumour cells were found in pleural or peritoneal fluid. The cells were characterized by the frequent presence of 'bull's-eye' vacuoles, in which a central spot was deeply stained by Giemsa, eosin or periodic acid-Schiff (PAS). In one of these it was shown by electron microscopy that the vacuoles are lined by microvilli, and that their mucinous content is condensed in the central area, presumably as a result of failure to discharge the secretion.

Aged↗
PubMed1974

A membrane filter method for correlating colposcopic, histological, and cytological pictures: the application to nuclear DNA measurements.

A method is described for collecting cells on membrane filters in their natural topographical relationships, so that they can be correlated with exact areas in the cervix and with punch biopsy specimens. The same cell sample, after study with Papanicolaou stain, can then be used for other methods without the cells losing their spatial relationships. An example is given of an early cervical carcinoma in which, using a photographic method with a simple type of photometric device, the nuclear DNA was measured from accurately identified normal and neoplastic areas.

Biopsy↗