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A Ia Chizhov

Publications and source records attributed to A Ia Chizhov.

At least 19 recordsLinked to original sources
PubMed2003

[Classification of hypoxia, hypo-, and hypercapnia].

The new classifications of hypoxical, hypo- and hypercapnical conditions are elaborated. They take into account the ecological factors in the development of various kinds of exogenic hypoxia, hypercapnia. For the first time the positive sides of physiological hypoxia and hypercapnia are brought in. In all classification til the last days hypoxia was considered as pathological process only. However hypoxia can be met in different physiologic conditions of organism: internal period of fetus development, hard physical work, increased sportsmen activity, hypoxia after hearty meal, hypoxia of aged organism. The same it is possible to say about the hypo- and hypercapnical conditions.

Adaptation, Physiological↗
PubMed1999

[The adaptational intracellular mechanisms regulating energy homeostasis during intermittent normobaric hypoxia].

Rats trained to intermittent normobaric hypoxia (INH) developed an increase of the glycogen contents in the heart and liver parenchymatous cells. Fatty acids seem to be the main source for synthesis of the intracellular glycogen. The intracellular transformation of the lipid energy substrate into the carbohydrates maintains the energy homeostasis in hepatocytes and cardiomyocytes during hypoxic intervals of the INH thus creating the necessary conditions. This kind of regulating the substance supply of the cell energy supports the organism stability under various effects.

Adaptation, Physiological↗
PubMed1994

[The possibilities of using intermittent normobaric hypoxia for treating hypertension patients].

The response to intermittent normobaric hypoxia (INH) created in breathing gas hypoxia mixture (10% oxygen, 90% nitrogen) was evaluated in 123 patients with essential hypertension stage I and II. Hypoxia adaptation effects on central hemodynamics, physical performance, kinetics of oxygen exchange were studied. A pronounced response to INH persistent for 6 months was demonstrated in 80.5% of the patients. The reduction of the arterial pressure resulted from different mechanisms depending on hemodynamic type. Physical performance of the patients rose, oxygen consumption and transport normalized.

Adult↗
PubMed1992

[The characteristics of the hemodynamics and oxygen regimen of the rat uterus].

For biomicroscopic study of architectonic and hemodynamic features of uterine vascular bed wide ligation was carried out. It is shown that the vascular bed serves for blood deposition with cyclic change of inflow and outflow intensity. A rhythmic hypoxia results in a decrease of PO2 in the myometrium. The revealed biorhythm is considered evolutionary, determining physiological mechanism of plastic supply of generative function and development of the fetus resistance to hypoxia.

Animals↗
PubMed1990

[The diagnostic and prognostic significance of transcutaneous PO2 dynamics during a functional test in "pretoxicosis" and the initial stage of gestosis].

This study has simultaneously examined the kinetics of oxygen metabolism (KOM) and clinical symptoms of "pretoxemia" and edema of pregnancy. It was found out that estimates of KOM obtained before and after the hypoxia test may allow identification of abnormal tissue respiration typifying "pretoxemia", differentiation between "pretoxemia" and early-stage late toxemia (edema of pregnancy), and prediction of the risk and time of late toxemia, and potential of the body to adapt to hypoxia. Evaluation of KOM before and after the hypoxia test may be employed as a test for subclinical late toxemia.

Blood Gas Monitoring, Transcutaneous↗
PubMed1989

[Kinetics of oxygen metabolism in pregnant women with high risk of developing late toxemia during intermittent normobaric hypoxia].

Oxygen metabolism kinetics (OMK) was investigated in 90 pregnant females with high risk for late gestoses and associated vascular disorders (essential hypertension, stage I, and neurocirculatory asthenia of hyper- and hypotonic type) exposed to preventive treatment with intermitting normobaric hypoxia (INH). The study revealed that initial disorders of tissue respiration were featured with compensatory stimulation of tissue oxygen consumption. In early signs of late gestosis the consumption intensity was found to be diminished. During INH treatment course there was an evidence of normalization in oxygen metabolism. The time-course of OMK values permitted to assess the level of systemic adaptation to hypoxia in pregnancy. INH technique was proved to be an efficient nonpharmacological method of late gestosis prevention.

Female↗
PubMed1989

[Preventive use of intermittent normobaric hypoxic hypoxia in pregnant women at high risk of developing late toxicosis].

The authors studied the efficiency of preventive usage of intermittent normobaric hypoxic hypoxia (INHH) in 44 pregnant females at high risk for late gestosis in presence of essential hypertension, stages I-II, and hypertensive type of neurocirculatory asthenia. The authors paid attention to a decrease in the incidence of late gestosis, its severe patterns especially, and perinatal mortality.

Adult↗
PubMed1989

[Changes in the functional status of lymphocytes in patients with chronic salpingo-oophoritis treated by normobaric hypoxia].

Therapeutic exposure to normobaric hypoxia improves both clinical and laboratory parameters in patients with chronic salpingo-oophoritis. The unidirectional trend of change is due to normalization of major systemic functions, including lymphocyte activity, owing to the recovery of lymphocyte metabolism and redistribution of T cell subpopulations towards a greater proportion of T helper cells. Adaptation to a moderate hypoxic stimulus is a promising physiologic method of improving nonspecific systemic reactivity.

Adult↗