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Biomedical subjects

A Ia Kormer

Publications and source records attributed to A Ia Kormer.

33 records · Page 2Linked to original sources
PubMed1983

Biomedical aspects of cardiac massage in experiments and clinical practice.

Despite current successes in modern cardiology and heart surgery, the problem of restoring and maintaining cardiac function in cases of sudden arrest or ventricular insufficiency is still urgent. Different methods of mechanically assisting the heart and replacing its pumping function exist, and direct mechanical cardiac massage (DMCM) is one of the more important. Experimental results with dogs and calves on 2- to 4-h DMCM, cardiac massage lasting for up to 48 h, subsequent restoration of cardiac activity, and cardiac massage during experimentally induced myocardial infarction permitted clinical application in patients with myocardial infarction complicated by ventricular fibrillation. DMCM also permits extension of the possibilities of obtaining and transplanting donor organs. It is one of the variants for solving the problem of total and partial replacement of the pump function of the heart, and now makes it possible to solve some important problems in transplantation and cardiac resuscitation.

Animals↗
PubMed1982

[Hemosorption as a treatment method in digitalis poisoning of heart failure patients with myocardial infarct].

Results of haemosorption in treating digitalis intoxication are analyzed. In 2 patients haemosorption was used for 90 min at the volume speed of 100 ml/min. Digoxin clearance at the start of haemosorption was 98.4 and 83.8 ml/min, at the end 85.7 and 70.3 ml/min. Digoxin concentration decreased by 44.8 and 13.0%. Hemosorption enabled performing electric defibrillation with restoration of the sinus rhythm.

Aged↗
PubMed1979

[Maintenance of the circulation and the restoration of heart function in the donor body by means of direct mechanical heart massage for subsequent transplantation (an experimental study)].

The possibility of maintenance of circulation and subsequent restoration of the function of the heart in the organism of the donor, after 10-minute arrest of circulation, for transplantation of the heart was investigated. Study of the hemodynamic, biochemical, metabolic, and structural changes in the myocardium after 2-hour mechanical massage without and with pharmacological protection of the myocardium (glucose--insulin--potassium, hydrocortisone, dipyridamole), without and with restoration of cardiac activity in the organism of the donor and the recipient after transplantation of the second heart by the method suggested by Moory et al. in artificially created left ventricular insufficiency showed that direct mechanical massage of the heart may be used for its short-term preservation in the donor organism.

Animals↗
PubMed1977

[Experimental autotransplantation of the heart].

The paper analyses the results of 15 heart autotransplantations undertaken in puppies under deep hypothermia. The employed method of autotransplantation without division of the atrial septum is described. The characteristics of a adaptation of the cardiac autotransplant in the recipient body are presented along with the principles of correction of the changes observed in the early postoperative period.

Animals↗
PubMedDate not supplied

[Interpretation of the kinetocardiogram of the right heart].

On the basis of ultrasonic Doppler valvulocardiography of 20 healthy men and catheterization of the right heart of 15 patients with acute large-focal myocardial infarction, the development of elements of the right kinetocardiograms (KCGr) is explored. Comparison of kinetocardiograms of the right heart with ultrasonic and catheterization data has demonstrated that KCGr can be used to examine right heart contractions of cosmonauts and pilots in flight and on the ground as well as of patients to diagnose pathologies of the right compartments of the heart.

Adolescent↗
PubMedDate not supplied

[Anesthesiological management in transplantation of the heart after temporary mechanical substitution of its function].

The first experience of anesthesiological management of three two-step orthotopic heart transplantations is reviewed. As the first step of surgical treatment one recipient was implanted an artificial heart "POISK-IOM" (Russia), in 2 other patients left ventricular bypass was achieved using a "Biopump" ("Biomedics", USA). Anesthesia techniques, methods of infusion-transfusion therapy, and other components of intraoperative management are described. Hemodynamics, donor heart function recovery, and other homeostasis parameters have been analysed. It has been noted that high doses of fentanyl in combination with ketamine and diazepam ensured satisfactory course of general anesthesia. There were no cases of intraoperative lethality. A more complex aspect of anesthesiological management was correction of various homeostasis disturbances which progressed during surgery in patients with left ventricular bypass. In two cases the intraoperative period was characterized by the onset of multiorgan failure (heart, respiratory, renal failure, metabolic disorders, coagulopathy), which played a negative part for the postoperative period of heart transplantations. It is concluded that prediction of possible complications during temporary mechanical replacement of the cardiac function and timely determination of contraindications for the second step of two-step heart transplantations are the most important trends of investigations for anesthesiologists, intensive care specialists, and transplantologists.

Adult↗
PubMedDate not supplied

[The hemodynamics of the lesser circulation before and after heart transplantation in patients with dilated cardiomyopathy].

Studies of the lesser circulation hemodynamics in 150 patients with dilatation cardiomyopathy and in 15 after heart transplantation revealed secondary postcapillary pulmonary hypertension of more than 60 mm Hg in cases with dilatation cardiomyopathy with systolic pressure in the pulmonary artery (SPPA) in 30% of patients, transpulmonary gradient (TPG) of more than 15 mm Hg and pulmonary vascular resistance (PVR) or more than 4 Wood's U in 15.3% of patients. Two stages of pulmonary hypertension in dilatation cardiomyopathy should be singled out: I with SPPA of 60 mm Hg, TPG of 15 mm Hg, and PVR of less than 4 Wood's U, and II with SPPA of more than 60 mm Hg, TPG of more than 15 mm Hg, and PVR of more than 4 Wood's U. Orthotopic transplantation of the heart is indicated for patients with Stage I pulmonary hypertension. For patients with Stage II condition prolonged inotropic and vasodilator therapy is necessary, and if it fails, heterotopic transplantation of the heart or transplantation of the heart and lungs should be resorted to. The basic characteristics of the lesser circulation reflecting the reversibility of pulmonary circulation disorders are SPPA, TPG, and PVR. Failure of prolonged inotropic vasodilator therapy may be indicative of irreversible injury to pulmonary vessels. Lesser circulation hemodynamics usually normalizes a month after heart transplantation. If TPG is less than 15 mm Hg and PVR less than 2 Wood's U, the incidence of reversible posttransplantation right-ventricular insufficiency depends on SPPA pretransplantation level. Mortality because of right-ventricular insufficiency was 8.33%. One-year survival after heart transplantation is related to preoperative TPG and PVR values.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗