[First case in Russia of coinfection of visceral leishmaniasis and HIV-infection].
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Biomedical subjects
Publications and source records attributed to A Ia Lysenko.
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Specific features of the course of Leishmania and Pneumocystis infections were studied on experimental models. Laboratory animals were subjected to medicinal suppression with Tricort-40. Leishmania infection in naturally susceptible animals was considerably aggravated (in comparison with the controls) in the presence of even short-term immunosuppression. Pneumocystis infection developed in experimental animals under the effect of double suppression. The process of the reactivation of Pneumocystis infection was influenced by Leishmania infection, rapidly developing in the presence of prolonged immunodeficiency. The results thus obtained make it possible to regard Leishmania infection in animals with reactivated Pneumocystis infection as co-infection having the properties of a biological, immunosuppressant. Such situation may be extrapolated on HIV/visceral leishmaniasis co-infection.
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The paper deals with the topical problem of false parasitic diseases (FPD) in patients with various organic (somatic and mental) disorders. A classification of groups of FPD patients is given according to their clinical and social signs. Examples of 6 cases of FPD observed by the authors and those published in the literature are presented. Simple and effective recommendations on the management of FPD patients are given.
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