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Biomedical subjects

A Idowu

Publications and source records attributed to A Idowu.

7 recordsLinked to original sources

Effect of aqueous extract of miswak on the in vitro growth of Candida albicans.

Chewing sticks (miswak) which are the roots of Salvadora persica plant have been used for centuries as oral hygiene tools in many parts of the world particularly in Saudi Arabia. Many studies have demonstrated the antiplaque, antiperiopathic, anticaries and antibacterial effect of these sticks. This study was designed to investigate the antimycotic effect, if any, of the aqueous extract of the plant roots. Various concentrations of aqueous extract of miswak prepared with Sabouraud medium were inoculated with Candida albicans (oral isolate). These were incubated at 37 degrees C and the turbidity was determined by OD at 600 nm wavelength measured at specific intervals over a period of 48 h. Data show that the extract at a concentration of 15% and above, has a fungistatic effect for up to 48 h. This antimycotic effect was probably due to one or more of the root contents which included chlorine, trimethylamine, and alkaloid resin, and sulphur compounds.

Antifungal Agents↗

Evaluation of a computerised system for medical records in an accident and emergency department.

This paper deals with the impact of the installation of a computerised record and data handling system in an urban Accident and Emergency department. This system became fully operational on the 14th of August, 1989 and replaced the previous manual method of administration. The new system allows 'real time' handling of patient details and generation of letters to both specialists and general practitioners. Audit of the department workload and data generation for research are improved. The current situation is described as well as potential benefits and constraints of the system.

Attitude to Computers↗

Improvement of 8-arm maze performance in aged Fischer 344 rats with 3,4-diaminopyridine.

Short-term memory of a spatial task by male Fischer 344 rats at 3, 12, and 24 months of age was examined in a radial 8-arm maze. Performance by 24 month old rats was significantly poorer than that of 3 or 12 month old rats. 3,4-Diaminopyridine (1000 pmole/kg), a compound that stimulates acetylcholine release, significantly improved 8-arm maze performance by 24 month old rats. Thus, an age-related deficit in short-term memory for a spatial task can be ameliorated by a compound that stimulates acetylcholine release.

4-Aminopyridine↗