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Biomedical subjects

A Isaac

Publications and source records attributed to A Isaac.

22 records · Page 2Linked to original sources
PubMed1994

Gaze discrimination in patients with schizophrenia: preliminary report.

The authors administered a gaze discrimination task to 24 patients with chronic schizophrenia and 25 subjects with no psychiatric history. Each subject was shown slides and asked, "Is the person in the slide looking directly at you?" Patients with schizophrenia were more likely than comparison subjects to perceive the person in the slide as looking at them when the person was looking away. Because there is evidence that gaze discrimination performance involves the superior temporal sulcus region of the brain and this region has been implicated in theories about the pathogenesis of schizophrenia, further study of the gaze discrimination task seems indicated.

Adult↗
PubMed1989

Immunotherapeutic modulation of intraperitoneal adhesions by Asparagus racemosus.

The hypothesis that macrophages appear to play a pivotal role in the development of intraperitoneal adhesions and that modulation of macrophage activity, therefore, is likely to provide a tool for prevention of adhesions, was tested in the present study. Effect of Asparagus racemosus, an indigenous agent with immunostimulant properties, was evaluated in an animal model of intraperitoneal adhesions induced by caecal rubbing. Animals were sacrificed 15 days following surgery. The peritoneal macrophages were collected to assess their activity. At the same time, peritoneal cavity was examined for the presence of adhesions, which were graded. A significant decrease was observed in the adhesion scores attained by animals receiving Asparagus racemosus. This was associated with significant increase in the activity of macrophages (70.1 +/- 2.52), compared to that in surgical controls (53.77 +/- 10.8). These findings support our hypothesis and provide a novel approach for the prevention and management of post-operative adhesions.

Adjuvants, Immunologic↗
PubMed1988

The relation between diurnal changes in intraocular pressure and refractive power after radial keratotomy.

Diurnal changes in visual acuity are often reported by patients undergoing radial keratotomy. Refraction, keratometry, and intraocular pressure were measured, 3 times a day, in 15 eyes 3-6 months after radial keratotomy, in 11 eyes one year after surgery, and in 5 controls. Higher myopia in the evening was found in 73% of the patients. All of the changes in refraction, keratometry, and tonometry were not statistically significant. No correlation was found between diurnal changes in intraocular pressure and corneal refractive power. The subjective sensation of diurnal refractive changes is usually milder one year after the operation.

Adult↗