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Biomedical subjects

A Isacsson

Publications and source records attributed to A Isacsson.

At least 19 recordsLinked to original sources
PubMed2006

Variational treatment of the Shastry-Sutherland antiferromagnet using projected entangled pair states.

We have applied a variational algorithm based on projected entangled pair states (PEPS) to a two dimensional frustrated spin system, the spin-1/2 antiferromagnetic Heisenberg model on the Shastry-Sutherland lattice. We use the class of PEPS with internal tensor dimension D=2 , the first step beyond product states (D=1 PEPS). We have found that the D=2 variational PEPS algorithm is able to capture the physics in both the valence-bond crystal and the Néel ordered state. Also the spin textures giving rise to the magnetization plateaus seen in experiments on SrCu2(BO3)(2) are well reproduced. This shows that PEPS with the smallest nontrivial internal dimension, D=2 , can provide valuable insights into frustrated spin systems.

Journal Article↗
PubMed2002

Mechanical Cooper pair transportation as a source of long-distance superconducting phase coherence.

Transportation of Cooper pairs by a movable single Cooper-pair box placed between two remote superconductors is shown to establish coherent coupling between them. This coupling is due to entanglement of the movable box with the leads and is manifested in the suppression of quantum fluctuations of the relative phase of the order parameters of the leads. It can be probed by attaching a high resistance Josephson junction between the leads and measuring the current through this junction. The current is suppressed with increasing temperature.

Journal Article↗
PubMed2001

Coherent transfer of Cooper pairs by a movable grain.

Superconducting circuits that incorporate Josephson junctions are of considerable experimental and theoretical interest, particularly in the context of quantum computing. A nanometre-sized superconducting grain (commonly referred to as a Cooper-pair box) connected to a reservoir by a Josephson junction is an important example of such a system. Although the grain contains a large number of electrons, it has been experimentally demonstrated that its states are given by a superposition of only two charge states (differing by 2e, where e is the electronic charge). Coupling between charge transfer and mechanical motion in nanometre-sized structures has also received considerable attention. Here we demonstrate theoretically that a movable Cooper-pair box oscillating periodically between two remote superconducting electrodes can serve as a mediator of Josephson coupling, leading to coherent transfer of Cooper pairs between the electrodes. Both the magnitude and the direction of the resulting Josephson current can be controlled by externally applied electrostatic fields.

Journal Article↗
PubMed2001

Caring dynamics as perceived by staff supporting daily occupations for developmentally disabled adults.

This study addresses caring staff experiences of hindrances and help in the support of daily occupations among people with developmental disabilities. Data were collected by means of a questionnaire consisting of open-ended questions about the staff perceptions of their work experiences. The respondents (n = 81), corresponding to 94.1% of all care staff employed in a geographically defined care area in southern Sweden, worked in various day activity units supporting the daily occupations of their clients. A constant comparative method of data analysis was used. Staff expressions were classified in two main categories of caring dynamics: an operational level and a managerial level. Four areas were identified at the operational level: encountering realities of practice, attitudes to the clients and work demand, using the potential of knowledge and strategies and applying helping actions to the client. The managerial level included two areas, generalized work strategy and individualized work strategy. It is suggested that to develop the quality of interventions for supporting daily activities among persons with developmental disabilities, efforts should be made to identify caring dynamics as experienced by the caring staff.

Adult↗
PubMed2001

Diabetes and social conditions in Estonia. A population-based study.

BACKGROUND: The aim of this study was to investigate aspects of metabolic control, treatment and complications as well as quality of life in patients with diabetes mellitus from a defined population in Estonia. METHODS: We invited 220 randomly selected diabetes patients recruited to a clinical investigation from a local diabetes register of 1,100 patients in Viljandi, Estonia. The main outcome measures were derived from medical history, physical examination (height, weight and blood pressure), laboratory variables (blood glucose and glycated haemoglobin A1 (HbA1 normal reference range 3.2-5.6%), serum total and HDL cholesterol and creatinine), a questionnaire on disease-related knowledge and quality of life variables. RESULTS: In all, 181 diabetes patients were investigated, of whom 90% were diagnosed with type 2 diabetes. The mean diabetes duration was 8.9 years from clinical diagnosis and mean HbA1 level was 7.3%. The overall proportion of patients treated with insulin was 29.8% and with anti-hypertensive drugs 26.5%. Smoking was present in 14.3%. The proportion of patients with various diabetes complications was high (73.5%), mostly consisting of different manifestations of cardiovascular disease. Foot ulcers or gangrene were observed in 11.6%. A low level of quality of life was registered in many patients, mostly due to difficult living conditions. CONCLUSIONS: Diabetes patients in Viljandi showed an acceptable degree of glucose metabolic control, but reported a high degree of diabetes complications, as well as impaired quality of life. The diabetes complications may therefore be due to detrimental factors other than hyperglycaemia, e.g. the standard of care during previous years as well as current social and living conditions.

Adolescent↗
PubMed2000

Hand dermatosis in upper secondary school pupils: 2-year comparison and follow-up.

The purpose of this comparative study was to record the prevalence and to estimate the incidence of self-reported hand dermatosis in a cohort of upper secondary school pupils on two different occasions, in 1995 and 1997. A previously validated questionnaire was used. Of the 1273 pupils invited to participate, 1136 (89.2%) responded to the questionnaire. The 1-year prevalence increased, although not significantly, from 9.6% in 1995 to 10.5% in 1997. For girls, the 1-year prevalence increased significantly, from 12.4% to 15.7%, while for boys the 1-year prevalence decreased, but not significantly, from 6.7% to 5.1%. The cumulative incidence was significantly higher (P < 0.001) among the girls (10.5%) than among the boys (2.8%). Multiple logistic regressions showed that the highest risk factors for 1-year prevalence in 1995 were having self-reported childhood eczema, and a family history of atopic eczema or asthma. In 1997, the highest risk factors were self-reported childhood eczema, female gender and a family history of atopic eczema. This study has identified the point at which the genders diverge with regard to hand dermatosis, with boys tending to recover, while girls show a steady or even increasing prevalence.

Adolescent↗
PubMed2000

Direct care staff's need for support in their perceived work role in day activities units.

AIMS: This study sets out to investigate direct care staff's views of their need for support, supervision, and training in their practice in day care settings when supporting daily occupations among developmentally disabled persons. BACKGROUND: The first line staff are considered as having a prominent role in the successful delivery of service. METHODS: Three municipalities, one urban and two rural areas in southern Sweden, were chosen for the study. The studied population n = 81 consisted of 94.1% of all staff employed in day activities units supporting the clients' daily occupations or community-integrated, sheltered work employment. The data were collected by means of a questionnaire. FINDINGS: This material identified the staff's perceived work role, and their needs for support, supervision, and training in the areas of communication, environment adaptation, individual activation and training methods, with regard to learning disabilities and special needs. CONCLUSIONS: Care managers should focus upon preparation of staff support programmes to improve the quality and efficiency in this area of care.

Adult↗
PubMed2000

Impact of a cancer education multimedia device on public knowledge, attitudes, and behaviors: a controlled intervention study in Southern Sweden.

BACKGROUND: The objective was to determine the impact of a multimedia device offering information about malignant melanoma on public knowledge, attitudes, and behaviors. METHODS: Two municipalities in Sweden, Dalby and S Sandby, were chosen. The population of Dalby was exposed to the multimedia program during 1994-97, whereas the S Sandby population was not. A questionnaire was sent to random samples of the populations (10% of those aged 20-59 years) before (1994, n = 373 and n = 409, respectively) and after the intervention (1996, n = 375 and n = 418, respectively). Response rates were 74-89%. RESULTS: The groups were well balanced at baseline. In both areas women scored higher both at baseline and in 1996. Dalby women showed less fear of skin cancer in 1996 than in 1994 (2.13 vs 2.27, p < 0.01). This was not so in the controls. There was no major change in "sun behavior" in Dalby, whereas there was a negative change in S Sandby. After the intervention Dalby men had more "knowledge" (from 2.64 to 2.70, p < 0.05) and a tendency to better "sun behavior" (from 1.77 to 1.85, p = 0.076). There was no significant change over time in the S Sandby men. CONCLUSIONS: The multimedia program had a modest effect. The population in Dalby had more knowledge and changed its attitudes in a sun-protective direction. In the control area, the two-year follow-up sun behavior score was lower than at baseline. There was also significantly less fear of skin cancer after the intervention.

Adult↗
PubMed2000

Research methods courses for GPs: ten years' experience in southern Sweden.

At the Department of Community Medicine at Lund University we have given courses in basic research methodology since 1989. During a ten-year period, 138 (20%) of the 700 general practitioners (GPs) in our region completed the theoretical part of our course, 104 (75%) finished their research projects, and 17 signed up as PhD students at our department. Thus, we have provided a large number of GPs with a fundamental knowledge of research methods and we have recruited new PhD students to the field of general practice.

Curriculum↗
PubMed1999

Beliefs about health and illness essential for self-care practice: a comparison of migrant Yugoslavian and Swedish diabetic females.

In a multicultural society the frequency of contact with migrant diabetic individuals will increase, as well as the need for knowledge about their beliefs about health and illness, which have rarely been studied. The aim of the present study was to explore beliefs about health and illness among migrant Yugoslavian and Swedish diabetic subjects that might affect their self-reported self-care practices and care-seeking behaviours. The study design was explorative, and a purposive sampling procedure was used. Fifteen females born in Sweden and 13 in former Yugoslavia, aged 33-73 years, with previously known diabetes mellitus were recruited from primary health care centres in southern Sweden. Median time of residence in Sweden was 5 years (range 2-30 years). Eight of the Yugoslavians had their diabetes diagnosed in Sweden. Focus-group interviews including scenarios of common problems related to diabetes mellitus were held. Yugoslavian females in general gave less tangible examples concerning beliefs about health and illness. Yugoslavians were orientated towards feelings related to their migratory experiences, enjoyed life by making deviations from dietary advice and retaining former traditions, and were less inclined towards self-monitoring and preventive foot care. They also expressed a passive role, depending on health care personnel, and discussed the influence of supernatural forces. Swedes expressed themselves in terms of medicine and a healthy lifestyle, took active part in their self-care and let self-monitoring guide their actions. Self-care was mainly practised to restore health when ill in both groups, and when help was needed it was sought in the professional sector (nurse or physician). Yugoslavians expressed higher confidence in physicians and used more natural cure medicine, side by side with biomedicine, while Swedes more frequently used alternative medicine. Demonstrated dissimilarities illustrate that beliefs about health and illness differ between migrant Yugoslavian and Swedish diabetic individuals, and are essential for self-care practice and care-seeking behaviour and must be considered when planning diabetes care.

Adult↗
PubMed1999

Staff and administration perspectives in a one-year geriatric rehabilitation developmental process.

A health care reform for senior citizens took effect in 1992 in Sweden. Shortcomings as regards geriatric rehabilitation were identified and, in 1995, governmental grants were assigned to local developmental projects. The aim of this study was to report the staff and administration perspectives in a geriatric rehabilitation developmental process over a 1-year period. In all, 782 staff and 45 administration respondents took part. The investigation was based on questionnaires and series of interviews. Significant positive changes with respect to collaboration between the authorities involved were demonstrated at the administrative level, while the most positive results at staff level concerned competence development in the group of employees without college education. A positive process as regards geriatric rehabilitation has started in the study district, indicating that governmental grants assigned for the stimulation of developmental activities are beneficial. Official goals for geriatric rehabilitation, points of departure for the organization of rehabilitation services and the content of general and specialized rehabilitation programmes are pinpointed as some of the areas deserving further attention.

Aged↗
PubMed1998

Prevalence of self-reported hand dermatosis in upper secondary school pupils.

The purpose of the present study was to estimate the prevalence of self-reported hand dermatosis among upper secondary school pupils. All pupils in grades 1 and 3 from the four upper secondary schools in Växjö, southern Sweden, were invited to participate in the study. A previously validated questionnaire was used. Of the 2609 invited pupils, 2572 (98.6%) responded to the questionnaire. The point prevalence of self-reported hand dermatosis was 4.2% (95% CI, 3.4-4.9%) with no significant differences between gender and grades. The overall one-year prevalence of self-reported hand dermatosis was 10.0% (95% CI, 8.8-11.1%), i.e. the corresponding figures for males were 7.3% (95% CI, 5.9-8.8%) and for females 12.5% (95% CI, 10.6-14.6%). There were significant gender differences in grade 1 (p < 0.001) and in grade 3 (p < 0.05). Males and females from the hotel and restaurant course had the highest one-year prevalence in grade 3. It is concluded that the high point and one-year prevalence of hand dermatosis among upper secondary school pupils merits long-term prospective study in order to address the question of which aetiological or trigger factors are most important in the development of hand dermatosis in a population.

Child↗
PubMed1998

Quality in child healthcare. The views of mothers and public health nurses.

In child health promotion (CHP) programmes it is the public health nurse who is responsible for most of the work. However, the perspectives of the family and the staff must be identified in order to get a comprehensive picture of significant quality factors in child healthcare. One aim of this study was to assess the views of mothers and public health nurses concerning a CHP programme and the first home visit to parents of newborn children. Other aims were to compare mothers' and nurses' views of CHP programmes in relation to age, experience, structure of organization and urbanization, and mothers' views in relation to social position, health of the children, primi- or multipara, country of birth and urbanization. Two national postal questionnaires, one sent to the mothers (850), the other to public health nurses (291), yielded data for analysis. Both mothers' and public health nurses' views of what constitutes good child healthcare were found to concur with the official goals of child health promotion. Important quality indicators were said to be: kind treatment, competence, time, support, an all-round view, the individual perspective, and home visits to primipara parents.

Adolescent↗
PubMed1998

Acceptance by Swedish users of a multimedia program for primary and secondary prevention of malignant melanoma.

BACKGROUND: In Sweden, the incidence of malignant melanoma of the skin is rapidly increasing, and the disease is now one of the ten most common tumor types. The objectives were to apply multimedia techniques to increase public knowledge about malignant melanoma and its risk factors, to increase awareness of preventive measures, and to make people more disposed to change their sunbathing habits. METHODS: A trilingual (Swedish, English, and German) multimedia program was developed for two target groups, health care personnel and the general public, with a total of >500 "pages" in each language. User reactions were studied on-site at a municipal pharmacy and library, where the program was available in a kiosk with touch-screen. RESULTS: Practically all 274 users interviewed found the program easy to use and understand. 92% identified one or more of the recommendations given. 66% found the program information "worrying," and 29%--mainly young women-instantly declared that they were going to change their sun-exposure behaviors. No correlation to skin type was found. CONCLUSIONS: A multimedia program of the present design seems to be a useful tool for health promotion.

Adult↗
PubMed1998

Help-seeking patterns among parents with a newborn child.

In the child health promotion program in Sweden, the public health nurse is responsible for the majority of the work. The purpose of this study was to test the following hypotheses: (1) there are differences in CHP program utilization between mothers in different social positions; (2) there are differences in CHP program utilization between Swedish and foreign-born mothers; (3) there are differences in the way mothers in different social positions value formal and informal social support as a means for solving health problems; and (4) there are differences in the way Swedish and foreign-born mothers value formal and informal social support as a means to solve health problems. A random sample was drawn of 10% of all children born in a particular month. A national postal questionnaire was sent to 850 mothers with children about four to five months old. The response rate was 80%. The CHP program was utilized by 99.6% of the families. When given scenarios describing various problem situations, the mothers stated that they mostly would turn to the public health nurse irrespective of the type of problem. There was no support in this study for the first two hypotheses that there are differences in CHP program utilization between mothers in different social positions and between Swedish and foreign-born mothers. There was support in this study for the two last hypotheses that there are differences in the way mothers in different social positions and the Swedish and foreign-born mothers value nurses, other health care services, relatives/friends, and literature/mass media as a means to solve health problems.

Adolescent↗
PubMed1998

Occupation and survival: a 25-year follow-up study of an aging population.

OBJECTIVE: In this retrospective study of an elderly population cohort living in a defined Swedish rural area, the relationship between occupation and survival as a measure of objective health was investigated. The cohort has been followed for 25 years. METHOD: On the basis of the baseline socioeconomic interview from assessments performed when the participants were 67 years of age, an index of active participation in daily occupation was devised. The index was used to investigate the covariation between generic everyday occupation and long-time survival. RESULTS: For the female participants, Kaplan-Meier curves demonstrated differences in survival between the "less active" and "more active," and Cox regression survival analyses resulted in a significant covariance between occupation and survival. For the male participants, no such differences were found. CONCLUSION: The significant results for the women implied support for the core assumption of occupational therapy that a relationship exists between occupation and health. The lack of differences in survival among more active and less active men demonstrates the complexity of studying occupation.

Activities of Daily Living↗