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A Iu Grishin

Publications and source records attributed to A Iu Grishin.

3 recordsLinked to original sources

[Dual-factor correlation analysis of the distribution of morphofunctional properties of mitochondria].

Judging by double-factorial correlative analysis of mitochondrial morpho-functional property distribution during the treatment of organism with radioactive rays, it has been established that there is a high correlation between mitochondrial dimensions in population and known structural-functional types. To detect the force and tightness of this parameters' connection, there lists a method of double-factorial correlative analysis. The value of correlation coefficient lets assume that mitochondrial functional activity depends on mitochondrial dimensions and is described by straight regression equation. It has been established that dimension's increase is accompanied by mitochondrial functional activity decrease and vice versa, though some functionally inactivated mitochondria can have little dimensions. Thus, knowing mitochondrial dimensions in population we can detect it's functional properties and detect mitochondrial dimensions knowing the functional properties by straight regression curves.

Animals↗

[Three-factor correlation analysis of morphofunctional changes in mitochondria based on the results of morphologic and biochemical studies].

The multifactorial correlative analysis showed the tightness and correlative connection between the time after one time irradiation of experimental animals, breathing and redistribution of hepatocytes' mitochondria dimensions. It has been established that the velocity of mitochondrial breathing can be described by linear correlative dependences from time and area, negative coefficients in equations shows that the velocity of breathing decrease when time and mitochondrial area increase. This equations let to estimate mitochondrial population state, depending on time and their dimensions and show that big mitochondria perish in a more brief time. It was assumed that the velocity of destruction is depend on irradiation dose and it leads to the change of equation coefficients.

Animals↗