A Iu Ogurtsov | PubMed Health

PubMedDate not supplied

[A protocol of automatic alignment of genome sequences using the program OWEN].

A protocol of automatic hierarchical alignment of long DNA sequences using the program OWEN is described. The protocol is based on the command line regime of the program OWEN. The protocol makes it possible to align a large number of pairs of moderately similar sequences automatically. We used this protocol to align 8623 orthologous pairs of intergenic regions in human and murine genomes.

Animals↗

PubMedDate not supplied

[The properties of sequences involved in insertion and deletion mutagenesis in rodents].

We analyzed nucleotide sequences that were inserted to or deleted from genomic DNA during the divergence from common ancestor. The median length of these sequences is 3 nucleotides; they are enriched with palindromes and often repeat in adjacent DNA.

Animals↗