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Biomedical subjects

A Ivan

Publications and source records attributed to A Ivan.

At least 19 recordsLinked to original sources

Excess mortality--influenza epidemiological surveillance indicator.

Observations on "excess mortality" from influenza, carried out in the Moldavia area between 1957 and 1973, are presented in the paper. They made it possible to assess in time and space as well as in severity the knowledge on influenza epidemics. "Excess mortality" proved to be a valuable indicator of increase in influenza mortality, especially, on the occurrence of big epidemics the existence of which was closely related to the appearance of new types and variants of influenza viruses. Though "excess mortality" showed the highest values when death from acute pneumopathies recorded in the preepidemic and postepidemic periods was included in the calculation, it also pointed to the strong effect of influenza on all causes of death, especially chronic diseases of the respiratory and cardio-vascular systems.

Disease Outbreaks

Sources of hepatitis B virus infection in hospital environment.

Investigations on the incidence of hepatitis B antigen (HB Ag)-carriers among 1466 patients of 11 various hospitals and departments showed that sources of hepatitis infection were more numerous in hospitals for children than in those for adults. The high-risk departments were those of dialysis (5 out of 12 patients), clinical medicine (6.6%), and obstetrics and gynecology, for adults, and those of neuropsychiatry (17.9%) and clinical medicine (11.2%)for children . The highest incidence of HB Ag-carriers among the medico-sanitary personnel of 5 hospitals (436 sera) was recorded in a hospital of obstetrics and gynecology.

Carrier State

[Two decades of epidemiologic surveillance of the evolution of viral hepatitis in Iaşi County (1971-1990)].

The results of epidemiological observations on the evolution of viral hepatitis in the Iaşi district in the interval 1971-1990 are presented. A mean morbidity of 251.2 cases/100,000 inhabitants, this being in most years under the national mean, was found. In 75.9% of all cases the infections caused by hepatitis viruses affected the age-groups 1-14 years, indicating a high incidence of hepatitis A... Hepatitis B had a more increased incidence in the children aged 0-1 year, then it decreased but was present in all age groups. Although recorded all year round, increases in the incidence of viral hepatitis A were noticed during fall and winter seasons, prevailing in the children and teenagers collectivities.

Adolescent

[Preliminary data on possibilities for the early detection of risk for primary liver carcinoma in chronic HBsAg carriers].

The investigations on the risk of hepatocarcinogenesis in the HBsAg chronic carriers have suggested that the early detection of primary liver carcinoma requires epidemiological and laboratory follow up of their state of health. The preliminary results of the comparative investigations of 103 HBsAg carriers detected among blood donors and 93 controls without HBsAg are presented. Epidemiological inquiries, clinical examinations and laboratory tests (HBsAg, serum alpha-fetoprotein, alkaline phosphatase, gamma-glutamyltranspeptidase, glutamic-pyruvic transaminase, proteinogram, siderophilin, immunoglobulins M, A, G) were carried out. Elevated levels of alpha-fetoprotein, alkaline phosphatase and gamma- glutamyltranspeptidase were recorded in carriers as compared to controls (38.8% and 86%, respectively). The elevation of the levels of liver damage markers was significantly correlated, in the HBsAg carriers, with the carrier state over 3 years and less with the age-group. In the case of two carriers with elevated levels of alpha-fetoprotein (> 600-> 1,000 ng/ml) ultrasonography confirmed the suspicion of primary liver carcinoma.

Adult

[Epidemiological observations on the significance of the relations between elevated values of essential arterial pressure in schoolchildren and their parents].

The results of an epidemiological screening of 1,228 parents and 614 children, pupils in the V-XII forms of 12 schools of different types, are presented. It is suggested that when parents present elevated blood pressure values their children, although normotensive, are at high risk, especially in case more risk factors are present. The relation hypertensive parents--hypertensive offsprings was strongly significant. In the hypertensive children with normotensive parents the high frequency of some life-style dependent risk factors is discussed. The relationship between risk factors and morbidity by essential hypertension both in parents and their offsprings and the need of primary and secondary prevention programs for pupils are underlined.

Adult

[Epidemiological and laboratory observations on viral hepatitis morbidity in child social welfare institutions].

The investigations revealed that in the interval 1978-1987 the mean incidence of viral hepatitis type B in children was 40 at 100,000 inhabitants as compared to 767 in the children from orphanages. In 27.5% of the cases, the children from orphanages, with or without HBs antigen, had viral hepatitis in their case history. The prevalence of AgHBs carriers was of 21.6%, the highest value (46.1%) being recorded in the children from orphanages in the age group 0-3 years. It was also found that 14.9% of the children had AgHBs when admitted to orphanage and 28.7% became carriers later on. It is suggested that in children homes there are conditions for an increased risk requiring special measures for viral hepatitis prophylaxis and control.

Age Factors

[Epidemiological observations on alcohol consumption as a risk factor in essential arterial hypertension].

The results of the epidemiological investigations in industrial environment in view of demonstrating some relations between alcohol and salt consumption, tobacco smoking, over weight and prevalence of essential arterial hypertension are presented. The obtained data indicate that in 471 workers in smelting the prevalence of alcohol consumers (1-3 intakes/day of strong alcohol) was of 15% as compared to 28.4% in 559 workers in an unit for building equipment, 4% in the 1188 women, working in ready-made and knitted wear mills and 19.8 and 4.5% in men and women, respectively, working in administrative services. Both the prevalence of daily strong alcohol consumption and of the other considered factors are significantly increasing with age. An increased prevalence of alcohol consumption associated with tobacco smoking, salt consumption and over weight was found in the hypertensive subjects as compared to the controls. The obtained data are useful in elaborating primary prevention programs of essential arterial hypertension.

Age Factors