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Biomedical subjects

A J Brakkee

Publications and source records attributed to A J Brakkee.

At least 19 recordsLinked to original sources
PubMed1990

[Basic principles of compression therapy].

The empirically established positive effects of the compression in the syndrome of the chronic insufficiency of the veins are widely accepted. Nevertheless the theoretical interpretation of these effects is often difficult, and even, depending on the criterion chosen, contradictory results can be yielded, particularly with regard to the influence on the pumping function of the veins. The experiences concerning these compression effects are reported, taking into consideration the non-linear relation between venous pressure and volume of the extremities and paradoxical results are explained.

Bandages↗
PubMed1986

The measurement and modelling of the mechanical properties of human skin in vivo--I. The measurement.

The mechanical properties of human skin in vivo are studied by means of uniaxial strain measurements. In order to obtain a stress-strain relationship which is independent of the in vivo measuring configuration, values for the effective width and effective length of the loaded skin strip have to be known. By variation of tab width and tab distance in a few series of experiments on the same subject, these effective values are found. In order to obtain a time independent stress-strain relationship a correction procedure is introduced. In this procedure the time dependent (viscoelastic) effects are described and subtracted from the total response.

Biomechanical Phenomena↗
PubMed1986

The measurement and modelling of the mechanical properties of human skin in vivo--II. The model.

The stress-strain relationship for human skin in vivo has a characteristic non linear shape even for low loads. Considerations are given on the basis of which a structural model has been selected, in which the mechanical properties of corrugated collagen fibrils are involved. It is found that such a model can describe the experimental stress-strain relationship surprisingly well with only three free parameters. These parameters are related to basic collagen fibril properties such as stiffness, diameter and waviness. The role of elastin is likely to be negligible for the purely elastic properties of human skin in vivo.

Biomechanical Phenomena↗
PubMed1985

[Skin blood flow measurement in microangiopathic changes].

The classical Martorell-ulcer, which is--according to the original criteria--rather rare, is preceded and accompanied by characteristic microangiopathic signs, the so-called "Pigmented Praetibial Patches" (PPP's). These signs are of great diagnostic significance. In complicated pathology it is important to measure skin blood flow and especially the reactions on a temporary arterial occlusion and on the application of a vasodilating ointment. For this purpose a method is used, based upon measurement of heat transport in the superficial 1.5 mm of the skin.

Humans↗
PubMedDate not supplied

[Quantitative research into vascular function in the lower limbs when these are affected by chronic venous insufficiency or lymphoedema].

Plethysmographic measurements of calf blood flow and venous muscle pump functions have been carried out in two groups of patients. In the first group of patients with chronic venous insufficiency the post ischaemic reactive hyperaemia decreased with the degree of clinical severity. In the other group of patients with primary lymphoedema no hyperfunctionning of the arterial system could be found. In this group the venous pump function was markedly reduced.

Adult↗
PubMedDate not supplied

[Effects of compression on venous pressure and limb volume. Paradoxal results].

The effect of elastic stockings on the venous pump are discussed in normal patients as well as patients with chronic venous insufficiency. The effects of compression are explained taking into consideration the nonlinear relationship between venous pressure and volume of the lower extremity. Results that seem paradoxical are therefore better understood.

Bandages↗