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Biomedical subjects

A J Collinge

Publications and source records attributed to A J Collinge.

9 recordsLinked to original sources

Ultrastructure of hyphal tip bursting in Penicillium chrysogenum.

Hyphae around the periphery of colonies of Penicillium chrysogenum were subjected to hypotonic shock by flooding them with distilled water at 25 degrees C, which provoked bursting of hyphal tips. A minority of hyphal tips (26%) burst rapidly within 1.8 s of the flooding, but bursting continued to occur such that the majority of peripheral tips (51%) were found to have burst around colonies maintained in the flooded state for 2 h. Electron microscopy of burst tips indicated that cytoplasm was released through a small hole with a mean diameter of 337 +/- 70 nm formed at or near to the hyphal apex. Woronin bodies were observed amongst the cytoplasm extruded from such tips. Burst apices were found to be plugged with an irregular deposition of electron-dense material similar in appearance to that which has been observed plugging septal pores in ageing regions of this organism.

Cell Wall↗

Unequal retinal illuminance and the binoculus.

An investigation was carried out in the relationship between the position of the binoculus and the depth (transmittance) of a monocular filter. The method used relied on changes in motor function and the linearity of the relationship found by previous workers, who used purely visual techniques, was confirmed. Some anomalous results were found which remain unexplained.

Eye Movements↗

A possible physiological basis for ocular dominance.

An experiment is undertaken to investigate the relationship between "sighting" and motor dominance. A review of recent work on the neurophysiology of vision is carried out and an attempt to explain ocular dominance using this is made.

Dominance, Cerebral↗

Changes in the position of the binoculus with unequal retinal illuminance.

An investigation was carried out into the effect of a monocular neutral density filter on the position of the binoculus. Two experiments were used, and it is postulated that the difference in the results obtained is due to the presence of a motor component in one of the experiments.

Adaptation, Ocular↗

Hyphal wall growth in Neurospora crassa and Geotrichum candidum.

Growth of the walls of hyphae of Neurospora crassa and Geotrichum candidum was studied using longitudinal and serial transverse sectioning methods. Rigidification of the hyphal wall below the extension zone did not appear to involve the gross formation of a secondary wall since the transition from extensible to non-extensible wall was not associated with an increase in thickness. However, behind the extension zone the walls leading hyphae of N. crassa increased in thickness until eventually they attained a thickness which was up to five times that of the tip wall. A hypothesis of hyphal wall growth is proposed.

Cell Wall↗