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Biomedical subjects

A J Drinnan

Publications and source records attributed to A J Drinnan.

At least 19 recordsLinked to original sources
PubMed1979

Immunological cross-reactivity of oral non-streptococcal bacteria with mammalian tissue.

The presence of cross-reacting antigens between oral non-steptococcal bacteria and human and monkey tissue was investigated by indirect immunofluorescence. Rabbit antisera, prepared against 22 oral bacteria, were incubated with cryostatcut sections of heart, skeletal muscle, brain cord, liver, kidney, and skin. A cell wall antigen of Lactobacillus casei was shared with neuroglial brain cells, and an antigenic component of Propionibacterium acnes was shared with kidney glomeruli. Tissue-reactive antibodies were absorbed from the sera with preparations of both the homologous bacterium and tissue fractions.

Animals↗
PubMed1979

Odontophilately.

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History, 20th Century↗
PubMed1979

Odontophilately.

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Dentistry↗
PubMed1978

Randomized, double-blind study of levamisole in recurrent aphthous stomatitis.

A randomized double-blind study was designed to evaluate the safety and efficacy of levamisole in the treatment of recurrent aphthous stomatitis (RAS). Thirty patients, aged 9-65 years, were selected, based on a documented history of three or more episodes of RAS. Patients were instructed to take 150 mg of levamisole (or placebo) daily for 3 days at the onset of the first prodromal symptoms of an ulcer. The regimen was to be repeated for each new episode, but not more than once per week. At each episode patients were examined and evaluated as to number and duration of ulcers, interval between episodes, pain associated with ulcers, and side effects. Data on 24 patients were suitable for analysis. Of those patients receiving levamisole, six showed slight improvement and five were unchanged. Of those patients receiving the placebo, one showed a marked improvement, four slight improvement, six were unchanged, and two deteriorated. There was neither a clinical nor a statistically significant difference between the groups. It is concluded that levamisole, in this study protocol, had no effect on the incidence or severity of aphthous ulcers.

Adolescent↗
PubMed1978

Differential diagnosis of orofacial pain.

No attempt has been made to deal with all of the various diseases that the dentist has to consider when diagnosing orofacial pain. One of the most important causes of facial pain--so-called temporomandibular joint or myofascial pain dysfunction (MPD) syndrome--has not been mentioned, yet it accounts for many of the patients attending facial pain clinics. There are several textbooks devoted to the MPD and the reader is referred to these for a full description of the condition. Whenever a patient presents for evaluation of orofacial pain the dentist must remember: (1) to take a detailed history of the characteristics of the pain; (2) to complete a full examination of not only the teeth and the oral cavity but also the face, head, and neck; (3) not to assume that the patient in his chair necessarily has a dental condition producing his pain; (4) that if he is unaware of the existence of certain diseases he will never diagnose them!; and (5) to have no hesitation in referring a patient for evaluation rather than perform irreversible dental procedures.

Angina Pectoris↗
PubMed1977

Odontophilately.

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Dentistry↗
PubMed1977

Odontophilately.

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Child↗
PubMed1977

Eosinophilic ulcer of the tongue.

Two cases of tongue ulcers are presented. Histopathologic examination of biopsy specimens obtained from each case showed marked submucosal and muscular infiltration of polymorphonuclear eosinophils compatible with the diagnosis of eosinophilic ulcer of the tongue. The disease entity appears to be uncommon, yet, it should be recognized as benign since in both instances, healing was spontaneous.

Eosinophils↗
PubMed1976

Odontophilately.

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Dentistry↗
PubMed1976

Odontophilately.

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Dentistry↗
PubMed1976

Odontophilately.

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Animals↗
PubMed1976

Odontophilately.

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Dentistry↗
PubMed1976

Odontophilately.

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History of Dentistry↗
PubMed1976

Odontophilately.

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Dentistry↗
PubMed1975

Colitis after clindamycin therapy.

Colitis developed in a young patient who was receiving clindamycin as part of the management of pericoronitis. Vigorous treatment of the colitis became necessary. The case and the recent literature that has dealt with this potentially very serious complication of lincomycin and clindamycin therapy are reviewed. The dental profession should become aware of this dangerous side effect and exercise caution in prescribing any medication that could produce such a serious outcome.

Adult↗