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Biomedical subjects

A J Friedman

Publications and source records attributed to A J Friedman.

78 records · Page 5Linked to original sources
PubMed1984

Nongonococcal pelvic abscess caused by Salmonella enteritidis.

A 25-year-old patient presented with Salmonella enteritidis gastroenteritis and coexistent pelvic abscess caused by the same organism. After a failed trial of parenteral antibiotics, she underwent surgical therapy. S enteritidis is now documented as a specific agent in pelvic infection.

Abscess↗
PubMed1980

Rapid analysis of naphthalene and its metabolites in biological systems: determination by high-performance liquid chromatography/fluorescence detection and by plasma desorption/chemical ionization mass spectrometry.

A rapid procedure for the determination of naphthalene and its metabolites in bile of rainbow trout and mice is described. The integrated analytical techniques combine high-performance liquid chromatography/ultraviolet fluorescence detection and plasma desorption/chemical ionization mass spectrometry for identification and quantitation. After separation by reverse-phase liquid chromatography, naphthalene and its metabolites are detected and quantitated by ultraviolet fluorescence spectrometry. Identification of two metabolites is confirmed by mass spectrometry. A direct insertion probe tip for a conventional chemical ionization mass spectrometer was modified to obtain spectra of thermally labile compounds. A spectrum of less than 100 ng of naphthyl glucuronide, a labile glucuronic acid conjugate of 1-naphthol, was obtained with this system.

Animals↗
PubMed1980

Pregnancy in a patient with cystic fibrosis and idiopathic thrombocytopenic purpura.

A pregnant patient with cystic fibrosis and idiopathic thrombocytopenic purpura (ITP) is presented. Management of the pregnancy was complicated by the coexistence of the 2 diseases and consisted of antibiotic therapy, prolonged hospitalization, bed rest, exogenous pancreatic enzyme replacement, bronchodilators, blood and platelet transfusions, and high-dose steroids. A good outcome was obtained with cesarean section performed under local anesthesia at 32 weeks' gestation. Recommendations from the literature for the management of each disease are discussed.

Adult↗