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Biomedical subjects

A J Larner

Publications and source records attributed to A J Larner.

At least 127 records · Page 7Linked to original sources
PubMed1994

Congenital insensitivity to pain: a 20 year follow up.

The exact nosological status of "congenital insensitivity to pain" remains in doubt. Possible pathological correlates of this clinical syndrome include sensory neuropathy, central lesions at the level of the reticular formation or dorsal horn of the spinal cord, or a central indifference to, or asymbolia for, pain. The reassessment of two members of a kindred previously reported more than 20 years ago as having congenital insensitivity to pain indicated that they in fact had an inherited sensory and autonomic neuropathy. Prolonged follow up and morphometric analysis of sequential nerve biopsies may be necessary to definitively establish this diagnosis.

Adult↗
PubMed1993

Hyperthermia.

Explore the source record for details and available documents.

Heat Exhaustion↗
PubMed1992

Oesophageal candidiasis after omeprazole therapy.

Oesophageal candidiasis was diagnosed incidentally at endoscopy in two patients receiving omeprazole therapy. There were no other predisposing factors for the development of candidiasis. The infection was resolved rapidly by anti-candidal therapy and by stopping omeprazole. These findings suggest that gastric acid secretion and physiological reflux of acid into the oesophagus may play a protective role in preventing candida infection.

Aged↗