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Biomedical subjects

A J Libanoff

Publications and source records attributed to A J Libanoff.

11 recordsLinked to original sources
PubMed1976

Eosinophilia and endomyocardial fibrosis.

A 12 year old boy died after a 3 year course of recurrent and progressive heart failure. His cardiac symptoms began with a marked leukocytosis (white blood cell count 188,500/mm3) due to eosinophilia (90 percent). In 6 months, the leukocytosis and eosinophilia subsided, but the patient's heart failure progressed over the next 2 1/2 years. At autopsy there was no evidence of leukemia, but a severe endocardial fibrosis extending into the myocardium was found. The origin of endomyocardial fibrosis, although unknown, appears to have been related to the eosinophilia in this patient.

Child↗
PubMed1968

Atrioventricular pressure half-time. Measure of mitral valve orifice area.

In 20 patients studied by cardiac catheterization, the time required for the diastolic left atrioventricular pressure difference to fall to half its initial value (half-time) varied with the anatomic severity of the valvular stenosis. In mild mitral stenosis, the half-time was approximately 100 msec; in moderate stenosis, it was about 200 msec; and it was 300 msec or longer in severe stenosis. The half-time at the nonstenotic mitral valve was less than 25 msec. Although exercise increased the atrioventricular pressure gradient, heart rate, and cardiac output significantly, the half-time was affected only slightly. Mitral regurgitation of various severities did not affect the half-time. The half-time appears to vary inversely with the anatomic orifice area of the mitral valve. The determination of the half-time obviates the need for the commonly used exercise test for the evaluation of mitral stenosis.

Cineangiography↗