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Biomedical subjects

A J Lyne

Publications and source records attributed to A J Lyne.

13 recordsLinked to original sources

Vogt-Koyanagi-Harada syndrome, a rare association of Hodgkin's disease.

Vogt-Koyanagi-Harada syndrome (VKHS) is a well-documented clinical entity. We report the case of a 24 year old man who, within 5 months of the diagnosis of VKHS, developed Hodgkin's disease. Like VKHS, the aetiology of Hodgkin's disease is unknown. A viral factor has been suspected in the pathogenesis of both conditions. Similar immunological abnormalities have been described in both, and may be important predisposing factors.

Adult↗

Necrotizing scleritis after ocular surgery.

Six cases of acute necrotizing scleritis are described. These first presented after ocular surgery to the same eye and possible aetiological factors relating to the surgery are discussed. A mechanism for the production of scleritis in these cases is proposed which is analogous to an experimental animal model.

Adult↗

A disposable cannula for the aspiration of soft lens matter.

A double cannula is described suitable for the aspiration of soft lens matter. The cannula is a modification of a double irrigation needle already marketed and will be available in a presterilised disposable pack for use with disposable syringes.

Adult↗

Ocular effects of hyperbaric oxygen.

A series of 26 patients undergoing hyperbaric oxygen therapy for more than a month was examined. Eighteen of them showed a definite change in their refraction towards myopia. The amount of myopia varied from 0.5 to 5.5 dioptres. No other ocular effects were observed. It is considered that the change in refraction is due to increased refractive index of the lens.

Adult↗

Corneal sensation in scleritis and episcleritis.

A series of 59 patients were examined for loss of corneal sensitivity. Thirty-five of them suffered from scleritis and 24 suffered from episcleritis. There was a difference between the 2 conditions in that significantly more patients with scleritis were affected than patients with episcleritis. It was also found that among the scleritis patients there was a close relationship between the number of quadrants affected and decrease in sensitivity. Five patients had necrotising scleritis, and they all showed marked loss of sensitivity. Sensitivity returned to normal when the scleritis resolved except when a large area of scleral ectasia resulted. The test is of importance because it is one of the easiest methods of detecting the onset of necrotising scleritis in its earliest stages.

Cornea↗