Biomedical subjects
A J Maggio
Publications and source records attributed to A J Maggio.
Renal preservation with inosine.
Isosine improved post-transplantation function of canine kidneys subjected to thirty minutes of normothermic ischemia followed by flushing and twenty-four-hour cold storage. Inosine was not able to improve renal preservation when cold storage was extended to forty-eight hours after thirty minutes of normothermic ischemia.
Why Marshall-Marchetti operation works . . . or does not.
Vesicourethral suspension operations fail (1) when preoperative evaluation is insuffcient, leading to improper selection of patients; and (2) for technical reasons when anatomy is uncorrected (suture malplacement, suture breakage, and failure to release adhesions) or when anatomy is corrected (periurethral fibrosis, fistula, stone or granuloma formation on nonabsorbable suture, and overcorrection). Vesicourethral suspension operations work by changing urethrotrigonal anatomy, creating a new equilibrium of forces acting on the bladder neck and urethra.
Effects of preliminary normothermic flushing on hypothermic renal preservation.
Flushing of harvested kidneys with hypothermic perfusates is presumed to cause inappropriate circulation due to vasospasm. Effects of initial normothermic flushing prior to hypothermic flushing and cold preservation were tested in canine kidneys. Analysis of the perfusion characteristics revealed that a brief initial flushing with solutions at 37 degrees C. eliminates vasoconstriction and even facilitates subsequent hypothermic flushing. In amounts not exceeding 100 cc. it was not deleterious to transplant function. Larger volumes of normothermic flushing were proved to cause endothelial injury and resulted in poor transplant survival.
The role of vitamin D in idiopathic hypercalciuria.
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In situ flushing of donor kidneys: its technique and rationale.
In situ flushing of kidneys through an isolated segment of aorta was done on mongrel dogs. The 500 cc cold perfusate at 3 to 4C (delivered in 6 minutes) effectively cooled the kidneys to about 15C. This simplified technique of in situ flushing, its usefulness and rationale are discussed.
Tunica vaginalis autografting for Peyronie's disease: an experimental study.
Groups of dogs were studied at varied intervals after autografting of tunica vaginalis from the testes to cover excised patches of tunica albuginea of the penis. Postoperative cavernosography revealed neither ballooning nor chordee. Histologically, the grafts were well accepted and uniformly merged with the neighboring collagen tissues at 6 months. We propose that tunica vaginalis would be ideally suitable for autografting to the penis after excision of Peyronie's plaques.
Renal artery trauma.
The ability to preserve renal function in patients with renal artery trauma is a goal sought by all urologists. We have reviewed our own experience as well as data published in the literature to formulate guidelines concerning which patients should be treated with revascularization and what factors are most likely to make this procedure successful.