PubMed Health⌕ Search

Biomedical subjects

A J Montgomery

Publications and source records attributed to A J Montgomery.

6 recordsLinked to original sources
PubMed2001

PET measurement of the influence of corticosteroids on serotonin-1A receptor number.

BACKGROUND: The hypothalamic-pituitary-adrenal (HPA) axis and serotonergic system interact functionally. The modulatory effect of corticosteroids on 5-HT(1A) receptor number and function has been repeatedly demonstrated in preclinical studies suggesting that raised corticosteroid levels decrease 5-HT(1A) receptor number and function in the hippocampus. METHODS: We used positron emission tomography (PET) to quantify the number of 5-HT(1A) receptors in two studies, the first in normal subjects given a single dose of hydrocortisone using a random-order, double-blind, placebo-controlled design and second in patients treated long-term with corticosteroids. RESULTS: We did not find that exposure to elevated levels of corticosteroids in either the short or long term alters 5-HT(1A) receptor binding in the hippocampus or other brain regions examined. CONCLUSIONS: This study does not support the hypothesis that corticosteroids exert a major inhibitory regulatory control over the 5-HT(1A) receptor binding in the human brain.

Adult↗
PubMed1993

Developing a career trajectory: research and community service.

The faculty of historically black colleges and universities (HBCUs) assume a major role in educating the largest share of the country's minority students. These institutions have traditionally focused upon teaching and learning processes which most result in student successes; conversely, their faculty's focus has suffered a decreased emphasis in the areas of research and community service. The Project for Faculty and Community Enhancement (FACE) has been designed to meet this decreased interest and activity in the areas of research and community service. This article will discuss the design and effectiveness of Project FACE among nursing faculty at twenty-two HBCUs.

Black or African American↗
PubMed1986

Previously unreported abnormalities of dermal basement membranes and collagen fibrils in a patient with X-linked spondyloepiphyseal dysplasia tarda.

Electron microscopic findings of the skin biopsy of a boy with spondyloepiphyseal dysplasia tarda showed several novel features. The basement membrane of the epidermis showed focal irregular thickening and reduplication. The collagen fibres showed foci of fibrous long spacing collagen and marked variation in fibre diameter. Taken together these abnormalities have not been reported in any other condition.

Adolescent↗
PubMedDate not supplied

Student upward mobility: utilization of an educational support model.

Hampton University School of Nursing was funded by the Teagle Foundation in 1990 for four years and later expanded for an additional year to develop, implement and evaluate an innovative Individualized Educational Support Model for licensed practical nurses (LPNs) residing in Southeastern Virginia. Project staff assigned the Teagle Initiative developed a model program for LPNs seeking the Bachelor of Science degree in nursing. The Teagle model offers opportunities for advanced placement through National League for Nursing Mobility Examinations, CLEP, ACT-PEP, and challenge examinations; tutoring by faculty and peers; counseling by project staff for academic and financial aid, and other concerns as needed; socialization with other project students and generic students; monthly stipends to assist with additional expenses incurred when the adult student returns to school and an alternative admissions criteria for the LPN who may not meet all aspects of the Hampton University admissions criteria.

Career Mobility↗
PubMedDate not supplied

AIDS education: knowledge, sexual attitudes and sexual behavioral responses of selected college students.

The problem studied in this investigation was whether a behaviorally focused Human Immunodeficiency Virus (HIV)/Acquired Deficiency Syndrome (AIDS) Program affects the knowledge, sexual attitudes and sexual behavior of college students. Three hundred and six first- and third-year college students were included in the study from one university located in Southeastern Virginia. The sample was predominately female, African-American and between the ages of 16-22 years of age. Freshmen students were presently enrolled in the institution's HIV/AIDS education program, which was part of a required course. The class sessions consisted of a pretest prior to students completing the reading assignment and class discussion. During the regular class session, the researcher discussed the reading assignment, provided basic information about HIV/AIDS, its transmission, prevention and treatment, and at the end of the sessions administered a posttest. Junior students were administered a posttest only. No prior reading assignment or class session was provided. The data collected were analyzed in terms of significant differences, utilizing t-tests for paired and independent groups, factor analysis and an analysis of variance. The results of the study indicated that there was little effect of HIV/AIDS education programs on knowledge, sexual attitudes and sexual behavior.

Adolescent↗