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Biomedical subjects

A J Nollen

Publications and source records attributed to A J Nollen.

17 recordsLinked to original sources

[A Dutch family with hereditary joint symptoms; multiple epiphyseal dysplasia].

Multiple epiphyseal dysplasia is a rare disease with autosomal dominant heredity which affects the epiphyseal ends of long bones; it leads to severe destruction of the joints. A large Dutch family with multiple epiphyseal dysplasia is described with manifestations of clinical disease predominantly in the lower extremities.

Adolescent↗

[Pain in the forefoot: a support sole is no panacea].

Three case histories of a painful forefoot due to an uncommon disease are given: Freiberg's disease, Morton's neuroma and metatarsal stress fracture. The differential diagnosis of metatarsalgia should include these diseases, especially if no static deformities are found.

Adolescent↗

Supracondylar fractures of the humerus in children; a long-term follow-up study.

The late anatomical and functional results of the conservative treatment of supracondylar humerus fractures were retrospectively studied in 87 children. The average follow-up was 14.5 years; 59 percent of the patients were treated with overhead traction and 32 per cent with a plaster of Paris. The average hospitalization time was 17 days. Rereduction was necessary in 23 patients; 16 of them were primarily treated with overhead traction. The overall results according to Høyer's criteria were good to excellent in 83 per cent of all cases. These results were comparable with other series with long-term follow-up. Cubitus varus was the most common late complication. Incomplete reduction seems to be the most important cause of this complication.

Adolescent↗

[Hereditary onycho-osteodysplasia (HOOD)].

Hereditary onycho-osteodysplasia (HOOD) is an autosomal dominant condition, characterized by dysplasia of the nails and joints and extra bone formation at the os ilium. Nephropathy occurs in some families with HOOD. We discuss a patient's history and the results of the study of her family. The incidence of all important features of this syndrome is given. Finally, some methods of treatment and genetic counseling are discussed.

Child, Preschool↗

Effects of ethylhydroxydiphosphonate (EHDP) on heterotopic ossification.

The effect of EHDP medication was studied in 25 patients in whom heterotopic ossifications around the hip (19 cases) and elsewhere were resected. EHDP seemed to have a favorable effect on prevention of reossification and on function, particularly when ectopic ossifications were resected after total hip replacement. In all the patients, EHDP administration postponed mineralization of osteoid.

Adult↗

Fracture of hip endoprostheses.

The cases of two patients with a fracture of the stem of an endoprosthesis of the hip are reported. Reference is made to the possible biomechanical causes that may lead to such fractures. Apart from adequate surgical technique, the nature and the shape of the prosthetic implant deserve our full attention.

Accidents↗