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Biomedical subjects

A J P M Overbeke

Publications and source records attributed to A J P M Overbeke.

8 recordsLinked to original sources

[Questionnaires on the quality of life in other than the Dutch language used in the Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine): the translation procedure and arguments for the choice of the questionnaire].

OBJECTIVE: To determine how the authors of research published in the Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine; NTvG) translated the questionnaires that they used in other than the Dutch language and to review the arguments on the basis of which the authors chose the questionnaires used. DESIGN: Bibliometric study and a survey. METHOD: All of the authors who had published an article in the NTvG up to and including January 2006 in which a questionnaire was used that was originally not in the Dutch language were approached by means ofa survey. In this survey, they were asked about the translation procedure and the factors that had contributed to the choice of the particular questionnaire. RESULTS: The authors of 38 articles in which a translated non-Dutch questionnaire had been used returned 31 survey forms (response: 82%). Among the 31 authors, who had used a total of 39 questionnaires, 24 (77%) were aware of the proper translation procedure. Of the 9 authors who had translated the questionnaire themselves, 6 had used the technique of translation and back-translation. In the choice of the questionnaire used, an important factor for many authors (64%) was the use of the questionnaire in previously published comparable research. CONCLUSION: A large proportion of the authors (77%) was aware of the current guidelines for the translation of questionnaires.

Bibliometrics↗

[Emergency procedures for taking care of the victims of bomb attacks: logistical and medical aspects].

In The Netherlands the threat of terrorist attacks also exist. Both doctors and hospitals alike should be prepared for such attacks both on the logistical as well as the medical level. Most terrorist attacks are carried out with explosives. This results in many victims and in cases of explosions in closed or semi-closed areas, often results in complex medical problems in many of the victims. An explosion that occurs as the result ofa bomb detonating can result in 4 patterns of injury: the primary explosion injury caused by the pressure of the blast, the secondary injuries caused by flying debris, the tertiary injuries caused by the explosion wind, and the quaternary caused by heat and fire. Common injuries seen following an explosion include: lung damage, neurological damage, abdominal injuries, bone fractures and skeletal damage and crush-syndrome. The triage occurs at the site of the explosion as well as on arrival in hospital. One especially important aspect of this is the sorting and selecting between victims who are likely to develop complex problems and who therefore need to receive aggressive treatment in a specially equipped centre and those patients for whom the nearest emergency department will suffice their needs. The triage should be repeated considering the possibility that initial estimates on these points may have been wrong. Epidemiological research should be carried out for each attack in order to make an inventory of the number of victims, the injuries incurred, the assessment of the effects of the medical help received and an assessment of the effectiveness of the total aid received.

Amputation, Traumatic↗

[Deficient information in developing countries: Internet alone is no solution].

Health-care personnel in developing countries have poor access to information, partly because the books are out of date and journals and Internet access are lacking, and partly because the information that is available is not appropriate for the local situation. There is too little research aimed at the problems of the Third World. This is due to a lack of interest in Western countries and because local scientists have done too little research. Internet solves the problem of access to information for health-care personnel in large hospitals and institutes, but there is still a shortage of relevant information for them as well. The editorial boards of professional journals could make a contribution by facilitating the publication of relevant research. Health-care personnel in rural areas will remain dependent upon basic books. This basic component of the provision of information should continue to receive attention. For the time being, Internet will remain inaccessible for rural health-care personnel. One of the initiatives being undertaken in order to improve the provision of information to health-care personnel in developing countries is the distribution of the 'blue trunk library' of the WHO with a selection of more than 100 basic books in every trunk. A number of journals have also taken action: the BMJ Publishing Group offers access to its journals free of charge to the 118 poorest countries and the Canadian Medical Association Journal provides free copies to libraries in developing countries. Moreover, a number ofwebsites have been started with a view to enlarging the information for health-care personnel in the Third World.

Books↗

[Dutch authors in international medical journals are also authors of publications in the Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine)].

OBJECTIVES: To determine whether Dutch medical scientists who frequently publish in international journals with high impact factors also publish in Dutch in the Nederlands Tijdschrit voor Geneeskunde (NTvG). DESIGN: Bibliometric study. METHODS: By means of a search in Medline, the Dutch authors were selected who had published the largest number of articles in 20 medical journals with high impact factors from 5 different specialties: general medicine, surgery, dermatology, psychiatry and ophthalmology. Subsequently, it was determined how often these authors had published in the NTvG in the same period. Moreover, a countwas made of the number of articles the first authors of original articles in the NTvG in 1991 and 2000 had published in international journals in 1993-1997 and 1998-2002, respectively. RESULTS: A large proportion of the Dutch investigators with many publications in international journals also published in the NTvG: in 1988-1992, 46 authors wrote 219 international publications and 35 of these published 151 articles in the NTvG; in 1998-2002, 55 authors wrote 326 international publications and 41 of these published 145 articles in the NTvG. The proportion of original articles published by these authors in the NTvG was lower than in the international journals: 83% for the international journals in 1998-2002 versus 39% for the NTvG in 2000. In 2001, 93 original articles by 87 different first authors appeared in the NTvG. Of these 87 authors, 67 (77%) published at least one article and 18 (21%) published more than 10 articles in an international journal in the period 1998 to 2002, as either the first author or a co-author. CONCLUSION: Authors that publish many articles in frequently cited international journals also write articles for the NTvG and, vice versa, the authors of articles in the NTvG also publish in international journals.

Authorship↗

[Registration of clinical trials: a statement from the International Committee of Medical Journal Editors].

Altruistic motives and trust are central to scientific investigations involving people. These prompt volunteers to participate in clinical trials. However, publication bias and other causes of the failure to report trial results may lead to an overly positive view of medical interventions in the published evidence available. Registration of randomised controlled trials right from the start is therefore warranted. The International Committee of Medical Journal Editors has issued a statement to the effect that the 11 journals represented in the Committee will not consider publication of the results of trials that have not been registered in a publicly accessible register such as www.clinicaltrials.gov. Patients who voluntarily participate in clinical trials need to know that their contribution to better human healthcare is available for decision making in clinical practice.

Clinical Trials as Topic↗

[Fraud in fundamental and clinical investigations. The necessity for an independent commission for scientific integrity].

Scientific misconduct takes various different forms and is real fraud only if there is evidence of intention. There are many forms of scientific dishonesty ranging from very serious to just below the limit of what is permissible, and it occurs at all stages of scientific research. Tracing fraud is by no means easy and its discovery is often only accidental. American, British and Dutch incidences are reported. We know the causes of fraud to be profit-seeking in all its forms, vanity and sloppy research practice. Oddly enough, the consequences of fraud are often more advantageous to the perpetrators than to the whistle-blowers. Literature becomes polluted and faith in scientific knowledge is damaged. In summary the measures and sanctions employed to combat fraud in the United States, Scandinavia, the United Kingdom and The Netherlands, are described. In The Netherlands are recently two commissions appointed. Points of discussion include: a governmental or other commission organized at a national or regional level, what protocol should be implemented, should the commission have powers of sanction, for how long should the members of commission be appointed and how is the extent of their liabilities to be decided upon?

Ethics, Research↗

[Reporting of scientific misconduct in health care research].

The incidence of scientific dishonesty in the Netherlands is not known, yet experiences at both the NWO (the Netherlands Organization for Scientific Research) and Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine) indicate that there must be several cases per year. For scientific fraud to be prevented students and researchers should receive thorough teaching, and in research laboratories an emphasis should be placed upon integrity. The Academic Medical Centre in Amsterdam has published a research protocol which is perfect for internal use. The Royal Netherlands Academy of Arts and Sciences publishes brochures on good research practice for researchers, teachers and students. The NWO and the Vereniging van Universiteiten (Dutch Association of Universities) have set up a committee for scientific integrity to function as a fallback mechanism and to assess the institutional procedures or to repeat the inquiries. As healthcare research institutions other than universities are involved since authorities are not always objective, an independent committee has been established to assess complaints about scientific dishonesty, the Scientific Integrity Health Research. Like the Committee on Publication Ethics it will publish its cases anonymously on an annual basis. Its judgments will be communicated to the people involved and the proper authorities.

Authorship↗