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Biomedical subjects

A J Prosser

Publications and source records attributed to A J Prosser.

12 recordsLinked to original sources

Automated high-performance purification of surfactant solutions: study of convective-enhanced adsorption.

Due to the amphiphilic nature of surfactants, they generally contain traces of their more surface-active parent components irrespective of the as received surfactant's label declaration. These trace impurities are preferentially enriched in the surfactant's adsorbed layer. To attain the state of "surface chemical purity" that implies the absence of impurities in the adsorbed layer, we had developed an automatic high-performance purification apparatus years ago. Here we put forward an improved version of this successful technique that considerably reduces the time required to purify surfactant solutions by accelerating the adsorption through convection. The advantages and reliability of the new technique are demonstrated by the purification characteristics of different solutions of as-received surfactants of varying degree of purity. As the overall time gained with convective purification is of 1 order of magnitude, the improved technique is particularly favorable for surfactant solutions that are prone to hydrolysis or degradation.

Journal Article↗

Articular fractures of the distal scaphoid.

We propose an anatomical classification of fractures involving the distal articular surface of the scaphoid. The predominant patterns, in the 37 patients reviewed, were avulsion fractures from the radio-volar tip of the tuberosity and impaction fractures of the radial half of the articular surface. The possible mechanisms of injury are discussed.

Adolescent↗

Pulmonary insufficiency after long bone fractures: significant correlation with the catabolic response.

Twelve young men between the ages of 17 and 25 years had their metabolism investigated over the first 5 days after sustaining multiple fractures involving at least one femoral shaft. Five patients developed respiratory distress and three of these required varying periods of ventilatory support. The lowering of arterial oxygen tension following injury was directly proportional to the excretion of urinary urea (a convenient index of protein catabolism). Pulmonary insufficiency was rectilinearly related to the degree of thrombocytopenia. The relationship between hypoxaemia and protein catabolism following long bone fractures has not been reported previously. It is important to appreciate that metabolic alterations are more severe in those patients with overt pulmonary insufficiency and that the metabolic response does not appear to be directly related to the severity of skeletal injury.

Adult↗

Spinal infection with Mycobacterium xenopi.

M. xenopi is well recognised as a pulmonary pathogen, but musculoskeletal infection is rare. Spinal infection is reported in a patient with systemic lupus erythematosus who was on corticosteroid therapy.

Female↗