PubMed Health⌕ Search

Biomedical subjects

A Jünemann

Publications and source records attributed to A Jünemann.

At least 19 recordsLinked to original sources
PubMed1995

[Intraocular pressure after filtering operation or combined filter-cataract operation].

BACKGROUND: The prevalence of glaucoma is 2% and of cataract 25% in patients at the age of 65 to 75 years. To this moment the discussion is open about the optimal therapy when there is simultaneous cataract and glaucoma. We evaluated and compared the intraocular pressure and the visual acuity in patients with filtering-surgery and combined surgery (= filtering surgery plus simultaneous cataract surgery). METHOD: In a retrospective study 56 eyes of 45 patients operated by filtering surgery and 46 eyes of 40 patients operated by combined surgery were examined. RESULTS: Patients with combined surgery showed significant higher frequency of fibrin in the anterior chamber compared to patients with filtering-surgery. After 12 months there was no significant difference in intraocular pressure between both groups. The IOP of the last examination was 16 +/- 4 mm Hg in eyes with combined surgery and 14 +/- 4 mm Hg in eyes with filtering surgery. Eyes with combined surgery showed an increase of visual acuity from 0.2 +/- 0.2 to 0.4 +/- 0.3, eyes with filtering surgery a decrease of visual acuity from 0.7 +/- 0.3 to 0.6 +/- 0.3. CONCLUSION: Combined surgery is perioperatively associated with a higher frequency of complications, but showed 12 months postoperatively equal values of regulated intraocular pressure.

Aged↗
PubMed1994

[Use of a new anomaloscope test in diagnosis of glaucoma].

BACKGROUND: The Color Vision Meter 712 (CVM) is a new automatic computerized anomaloscope relying on both the Rayleigh and the Moreland equation. In the present study the diagnostic value of Color Vision Meter was examined in glaucoma for the first time and was compared with the Farnsworth 100 hue test. PATIENTS AND METHODS: 33 normals, 15 patients with ocular hypertension (OHT) and a heterogenic group of 31 glaucoma patients were tested with the Nagel anomaloscope, the Color Vision Meter 712 and the Farnsworth 100 hue test. The following determinations were made in all subjects: 1. Anomalous quotient of the Rayleigh equation of the Nagel anomaloscope and of the Color Vision Meter, 2. Mean tritan score of 100 hue test, 3. The matching range, mid matching point, and anomalous quotient of the Moreland equation with the Color Vision Meter. RESULTS: While in the OHT group only the matching range of the Moreland equation was enlarged, all three variables (matching range, mid matching point and anomalous quotient) of the Moreland equation were significantly changed in the glaucoma group. The mean tritan score of the 100 hue test showed in the OHT group only a slight difference compared to normals, and in the glaucoma group a low significance and a low sensitivity. The matching range of the Moreland equation seems to be most useful with a sensitivity of 87.1% and a specificity of 93.6%. CONCLUSION: Our results show that the new anomaloscope Color Vision Meter 712 should be considered as a quick screening test for the examination of blue-color vision disturbances in glaucoma because of its higher sensitivity, its easier use for examiner and patients, and its shortened examination time (5 min per equation).

Adult↗
PubMed1994

VEP test of the blue-sensitive pathway in glaucoma.

PURPOSE: The blue-sensitive pathway in normal subjects and in patients with primary open-angle glaucoma (POAG) was tested with the pattern visual evoked potential (VEP) method under selective adaptation. METHODS: Recording of pattern-onset VEP in response to blue (460-nm) stripes (0.88 c/deg) presented either without or with a bright yellow (570-nm) adaptation light (Maxwellian view, 33 degree diameter). Amplitude and peak times were evaluated, and the mean tritan score of the Farnsworth 100-hue test was determined. Age-matched normal subjects (n = 34) and (n = 32) patients with POAG were examined. RESULTS: The amplitude and peak time of the VEP without selective adaptation did not discriminate normal subjects from the POAG group. With selective adaptation, the amplitude was reduced (P = 0.002) and its peak time delayed (P < 0.0001) in POAG, yielding a sensitivity of 75% and a specificity of 94%. The VEP measures only under selective adaptation correlated significantly in patients with POAG with the mean perimetric defect, with the optic disc damage, and with the 100-hue test. CONCLUSIONS: Recording the blue-on-yellow VEP is a useful test in glaucoma research.

Adult↗
PubMed1994

Peters' anomaly.

Explore the source record for details and available documents.

Child, Preschool↗
PubMed1993

[Blue-sensitive VEP test in diagnosis of glaucoma].

BACKGROUND: Glaucomatous eye diseases can be associated in many cases with a disturbance of blue-color vision. Also visual evoked potentials (VEPs) can be altered in glaucoma. In the present study both tests were combined in order to increase the sensitivity of the method, i.e. the pattern VEP was examined under conditions isolating the blue-sensitive part of the visual pathway. METHOD: 34 normals, 14 patients with ocular hypertension (OHT), 15 patients with a so called pre-perimetric primary open-angle glaucoma (PPOAG), and 32 patients with primary open-angle glaucoma (POAG) were examined by presenting in the onset-offset mode blue stripe patterns 1. without an adaptive background light (blue- "black" pattern = BB) and 2. with an intensive yellow adaptation light (blue-on-yellow pattern = BY) suppressing the red- and green-sensitive cones. Amplitudes and peak times of the onset response were evaluated. RESULTS: BB responses are of positive, BY responses of negative polarity (inion-ear). In normals the latter responses are significantly larger and have a significantly longer peak time. While in the patients groups the BB responses were not significantly altered, the BY responses were significantly reduced only in POAG. The peak time was significantly delayed in both PPOAGs and POAGs. The BY peak time proved to be most significant: Sensitivity 87.1%, specificity 82.4%. CONCLUSION: The recording of the VEP with blue stimuli presented under selective yellow adaptation is a sensitive test for early glaucoma diagnosis.

Adult↗
PubMed1992

[Persistence and transient conjunctival pathogen colonization before planned intraocular interventions].

The risk of a postoperative endophthalmitis is influenced by the presence of a significant bacterial colonisation of the conjunctiva before intraocular surgery. Between February and August 1990 we performed conjunctival smears in 481 patients 1) on the eve of the operation and 2) just before planned intraocular surgery, to evaluate a persistent or transient microbial colonisation of the conjunctiva. 352 patients showed insignificant ("negative") and 129 patients a significant ("positive") bacterial growth in the first conjunctival smear. 96% of the patients (n = 336) had a negative result in both smears. 30% of the patients (n = 37) with a positive conjunctival smear showed a persisting bacterial colonisation, whereas 70% of the patients (n = 92) had a transient colonisation of the conjunctiva with a negative second smear. As a persisting microbial colonisation of the conjunctiva may be an important factor for the development of postoperative endophthalmitis, we recommend prophylactic conjunctival smears before surgery to diminish the risk of intraocular infections after surgery.

Bacteria↗
PubMed1992

[Leiomyoma of the iris--a clinicopathologic case report].

A 20-year-old white man demonstrated a 2-3 mm in diameter ball like, grey white vascularized tumor at 12h in the iris stroma adjacent to the sphincter pupillae OD. The tumor was excised by sector iridectomy. Light microscopically the tumor consisted of densely packed spindle-shaped cells with oval nuclei with granular eosinophilic cytoplasm. Electronmicroscopically numerous 9nm-filaments in parallel configuration were found, fusiform dense formations, basal membranes and pinocytotic vesicles. Positive immunohistochemical reaction for Actin, Desmin and Vimentin, negative for S100.

Actins↗
PubMed1991

[Morphometric and qualitative changes in corneal endothelium in pseudoexfoliation syndrome].

In a prospective study begun in March 1986, in 182 eyes with pseudoexfoliation syndrome (PES) specular microscopic endothelial cell photographs were taken with direct and non-direct specular microscopy in non-selected patients who had not undergone intraocular surgery. Age-matched cataract eyes with normal intraocular pressure served as a control group. Standard specular microscopic examination (Bio Optics LSM 2000 A and Clinical Specular Microscope Camera) to evaluate the endothelial cell count and the morphology and quality of the endothelium yielded the following results. In 4432 control eyes with normal intraocular pressure the cell count was observed to be age-dependent and to have an average value of 2302 +/- 394 cells/mm2, the cells generally had a regular arrangement. In 123 eyes with pseudoexfoliation syndrome there was a significant (p less than 0.001) reduction in cell count to 1812 +/- 297 cells/mm2. In 59 eyes with PES and manifest glaucoma there was a significant (p less than 0.001) reduction of the corneal endothelium to 1482 +/- 267 cells/mm2. The cell picture was composed of enlarged, regularly arranged cells. In addition, such endothelial changes as incomplete cell lesions, cell detritus and appositions were six times as frequent as in normal eyes. In 32% of the eyes affected by PES we found manifest glaucoma. The statistical evaluation (matched age groups ect.) was carried out by means of the Mann-Withney-Wilcoxon rank test.

Adult↗
PubMed1988

[Placental chorioangioma and fetal abnormalities].

We report on a postpartally decreased girl with several malformations: turricephalus, deep root of the nose, prognathism, choanal atresia, low-set dysplastic ears, fourth additional blood vessel originating from the thoracic aorta. Nearly 70% of the placenta consisted of multiple chorioangiomas. A possible correlation between fetal malformations and placental chorangiomas is discussed. There is no valuable reference to a hereditary component in the development of chorioangiomas.

Abnormalities, Multiple↗
PubMed1979

[Lymphographic visualization of the rectal lymphatic channels and nodes].

Injection of Lipiodol U.F. was effected in the submucosa of the rectum. Injection was done exactly 1,6 mm into the wall. This created a wheal from which reflux of the contrast medium occured. Up to 5 ml Lipiodol U.F. were injected in this manner. Roentgenograms were made in two planes after 2,4,8,24 and 48 hours; occasionally, oblique or spotfilm exposures were taken. Accumulation of the contrast medium began after only 2 to 4 hours, usually reaching its maximum after 12 hours. Thereafter, no further lymph nodes became apparent, so that radiographs taken at this time are representative of final stage. This procedure was carried out on 12 patients suffering from rectum carcinoma and on one patient with a villous adenoma. All tumors were located at a depth of 4 to 6 cm. The results are demonstrated by pictures. The lymph was found to flow longetudinally in the wall of the rectum. The order of appearence of the nodes was arbitrary. Due to the small size of the lymph nodes, no preoperative conclusion could be drawn as to wether or not they had become metastatically infested. The postoperative radiographs provided a check in the radicality of the operative procedure, especially in those cases in which lymph nodes had been clearly visible. Because of the viscosity of the contrast medium and because of the quantity that remained in the submucosa and was resorbed by the lymph channels, the method was self-limiting.

Adenoma↗
PubMed1978

[Diagnosis and therapy of acute penetrating myocardial injury (author's transl)].

Clinical signs of an acute penetrating wound of the heart not always are clear. Because of hemorrhage and reduced cardiac output during heart tamponade venous pressure not necessarily must be increased. If by pericardiocentesis an aspiration of blood is possible, diagnosis of a penetrating heart wound is of high probability; otherwise there is no diagnostic value of a negative pericardiocentesis. Only in a case of a very small cardiac wound pericardial drainage can be used as a sole therapeutic proceeding; clinical observation is mandatory and an emergency operation at all time must be possible. In most cases immediately thoracotomy with suture of the cardiac wound should be performed. Attention is necessary because of an injury of a coronary artery. Following this principle prognosis is good if the patient is reaching clinical treatment alive. Lethal outcome in 2 of our 12 reported cases in one of them is caused by refusing immediate surgical intervention by the patient himself, in the other by development of ischemic cardiac necrosis involving a papillary muscle after suturing a cardiac wound.

Acute Disease↗
PubMed1976

[A new method of demonstrating the regional lymph nodes of the urinary bladder (author's transl)].

Pedal lymphography as used up to now does not fully demonstrate the lymphatic drainage of the bladder. A new method is presented in which Lipiodol-Ultra-Fluid is injected into the submucosal layer of the bladder wall under endoscopic vision. In 27 endovesical lymphographies the following lymph nodes could be demonstrated: the anterior, lateral and posterior vesical, the obturator, the external and internal iliac and the common iliac nodes.

Cystoscopy↗
PubMed1976

[Results of gastric lymphography with particular reference to gastric carcinoma (author's transl)].

The regional lymph nodes of the stomach can be visualised radiologically by injecting Lipiodol Ultra-Fluid into the submucous layer of the stomach wall through a gastroscope. Lymphography was performed in gastrologically healthy probands (n = 10), in patients with gastroduodenal ulceration (n = 17), and in patients with gastric carcinoma (n = 35). In 28 of the gastric carcinoma patients the first order lymph nodes were demonstrated, in 21 cases the second order and in 15 cases the third order whereas defects in uptake indicated metastases in 16 patients which could be histologically confirmed in 13. Gastric lymphography may contribute to the indication for operation if metastases are suspected in the second and third order lymph nodes as nodes along the upper border of the pancreas and the coeliac trunk are very difficult to remove radically.

Female↗
PubMed1975

[Problems of the one- or two-stage operations of carcinoma on the left part of the colon (author's transl)].

260 radically operations of carcinoma of the colon were carried out from 1963-1972; 163 of these operations have been done on the left part of the colon. The results of the one- and two-stage procedures were compared with the related literature. 46.5 per cent of the resected lymphnodes were affected by carcinoma. An expanded resection was done in 24 cases complicated with tumour perforation in adjacent organs. Among 147 one-stage left-side resections 20 insufficiencies of the anastomoses (13.5 per cent) were observed. To protect the anastomoses in 8 cases a coecal fistula and in 4 cases a fistula of the transverse colon were performed. There was no insufficiency of the anastomose. In 4 cases of two-stage precedures insufficiencies of the anastomose were found at the extraperitoneal replaced anus. The mortality was found to be 11.6 per cent. Peritonitis occurred in 18 cases: after 6 right sited and 12 left sited resections.

Adolescent↗