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Biomedical subjects

A Jainkittivong

Publications and source records attributed to A Jainkittivong.

8 recordsLinked to original sources
PubMed1998

Herpes B virus infection.

Herpes B virus (B virus) infection is common in macaques. Primary infection of B virus in primates is similar to herpes simplex virus 1 infection in human beings, but B virus generally produces only mild localized lesions in its natural host. In human beings, however, B virus can cause severe infection that may lead to death from encephalitis. Contact with monkey saliva, tissues, or tissue fluids is the most commonly reported route of transmission of B virus; a single case of person-to-person transmission has been reported. Airborne transmission is postulated to have occurred as a result of clinical circumstances in two reported cases, but there is no strong evidence to support the hypothesis of aerosol infection. Because B virus infection in human beings is often fatal, awareness of the risk of B virus infection should be emphasized. Although B virus infection in human beings is rare, it is an occupational health risk in exposed health care workers and laboratory personnel. This review of the literature of B virus infection includes case reports and a discussion of the nature of the B virus, characteristics of B virus infection in primates and human beings, the treatment of human infection, and the implications for dental health care providers. This report also serves as an introduction of the disease to the dental literature.

Aerosols↗
PubMed1998

The relationship between salivary histatin levels and oral yeast carriage.

Candida species are common commensal inhabitants of the oral cavity. Human saliva contains antifungal proteins called histatins. We tested the hypothesis that oral yeast status is related to salivary histatin levels. Thirty subjects were divided into two groups based on the presence (n = 15) or absence (n = 15) of yeast on oral mucosa surfaces. Unstimulated and stimulated submandibular and sublingual and parotid saliva was collected from each subject. Salivary flow rates were measured and histatin concentrations were determined in the stimulated saliva samples. The yeast colony positive group showed lower median unstimulated parotid saliva flow rates as well as lower median concentrations of total histatins in submandibular and sublingual saliva. There was a negative correlation between yeast colony-forming units and unstimulated parotid saliva flow rates and between yeast colony-forming units and submandibular and sublingual saliva histatin concentration and secretion. The results suggest that oral yeast status may be influenced by unstimulated parotid saliva flow rates and by submandibular and sublingual histatin concentration and secretion.

Aged↗
PubMed1995

Evaluation of medical consultations in a predoctoral dental clinic.

OBJECTIVE: A patient's medical condition can affect the delivery of dental care. Medical consultation is indicated for dental patients whose medical history is uncertain or when physical assessment may indicate an untreated medical problem. The aims of this study were to evaluate the use of medical consultation and determine how it affects dental treatment plans in a predoctoral dental clinic program. STUDY DESIGN: Reviews of 147 medical consultation requests were performed. RESULTS: The main reasons for medical consultations were cardiovascular assessment (51.5%) and diabetic status determination (12.6%). In the cardiovascular assessment category, hypertension (48.1%) and heart murmur (17.9%) were primary concerns. Main dental concerns were the need for preoperative antibiotic prophylaxis (33.3%) and the use of vasoconstrictors (20.4%). Overall, 32.1% of medical consultations resulted in an alteration in dental treatment plans. As a result of medical consultations, 8% commenced their medical management. CONCLUSIONS: These results indicated that medical consultations could reduce the medical risk associated with dental procedures and unnecessary antibiotic prophylaxis. Therefore for many dental patients, good communication between dentists and physicians is essential for adequate care.

Adolescent↗
PubMed1994

Allergic stomatitis.

There are basically two types of hypersensitivity reactions involved in allergic stomatitis, type I immediate hypersensitivity, and type IV delayed hypersensitivity. The allergic stomatitides may present with clinical appearances that mimic classic oral vesiculobullous and ulcerative lesions. Differential diagnosis from specific mucosal diseases is important in the treatment of oral allergy. Precise history taking and the elimination of the causative agents will be necessary. The mechanisms involved in oral reactions, etiologic factors, clinical manifestations, and treatment of allergic stomatitis will be described and discussed in this article.

Anaphylaxis↗
PubMedDate not supplied

Effect of folic acid on human oral epithelium in vitro.

The cytomorphological effects of folic acid were studied using in vitro established human oral epithelium. It was demonstrated that a concentration twice that used clinically (200 micrograms/ml) did not induce marked cytotoxic reaction in the cultured cells. The most pronounced changes were observed in cultures exposed to 200 micrograms/ml folic acid both in primary culture and subculture. The cultures displayed areas of degenerating cells showing oedema and increased translucency of the cytoplasm, flattened cells with distinct tonofilaments and atypical mitotic figures. Identical changes were found in cultures exposed to 50 and 100 micrograms/ml folic acid but to a lesser extent than in 200 micrograms/ml. These changes indicated that folic acid increased the number of cells undergoing terminal differentiation. From this study we suggested that folic acid when applied topically may play a role in local stimulation of epithelial cell differentiation leading to enhanced healing of oral ulcers.

Cells, Cultured↗
PubMedDate not supplied

Necrotizing sialometaplasia: review of 127 cases.

A review of 127 documented cases of necrotizing sialometaplasia is presented, mainly focusing on 96 palatal lesions. Necrotizing sialometaplasia is a benign, self limiting inflammatory lesion of the minor salivary glands. The cause is unknown but it may be related to oral trauma, tobacco use or inadequate blood supply. Male (mean age 49.8 yrs) to female (mean age: 36.3 yrs) ratio is 2.31:1. Because the clinical and histologic features mimic malignancy, proper diagnosis is of utmost importance in order to avoid unnecessary and extensive surgery and radiation therapy. The lesion heals spontaneously, regardless of therapy in two to eight weeks.

Humans↗