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Biomedical subjects

A Javalet

Publications and source records attributed to A Javalet.

At least 19 recordsLinked to original sources

[Syringo-peritoneal shunt].

The pathogenesis of syringomyelia is still under discussion. The authors advocate the role of the pressure of the spinal C.S.F. whose flow can be directed from the perimedullary space into the cavity. This force is responsible for an hydrodynamic dissection of the cord, even in cases of foraminal syringomyelia. Therefore it is not efficient to draw the fluid from the syrinx towards the subarachnoïd space. The authors suggest a syringoperitoneal shunt. The present report is only a technical note, according to the poor number of cases operated by this way (4 patients) and to a too-short follow-up (2 years for the first case).

Catheterization↗

[Changes in plasma level of corticotropin after intravenous injection of metyrapone. Value of this test in pituitary pathology].

The Metyrapone was given, the morning, in perfusion intravenous of saline serum over 2 hours. A.C.T.H. levels were determined before and at 2, 4, 8 and 24 hours. Sixteen normal subjects adults served on controls with 1 g of Metyrapone. Sixteen other normal subjects with 2 g of Metyrapone are best responses. With this maximum dose 2 g were studied nine hypophysal adenomas with three low responses, three normal and three high responses; thirteen hypophysectomised subjects with very low peak value at 4 hours, and only two responses higher than the controls, five Cushing's syndromes with variable responses. The I.V. Metyrapone test seems to offer several advantages: it eliminates the questions about gastro-intestinal absorption of Metyrapone (oral) and the difficulties of urine collection. With the A.C.T.H. dosage on 4 hours, this is a rapid test able to put in combination other hypophysal tests.

Adrenocorticotropic Hormone↗

Role of the pneumo-encephalogram in the diagnosis of spontaneous subarachnoid haemorrhage.

The authors have collected eighteen cases of primary intraventricular lesions revealed by a subarachnoid haemorrhage. Among these cases, the most important are the choroid plexus papillomas followed by ependymomas; some cases have no precise histological interpretation. Generally speaking, cerebral arteriography gives only indirect evidence of ventricular dilation and thus does not confirm the presence of a lesion. On the contrary, the pneumoencephalogram is consistantly positive, but does not give the differential diagnosis between intraventricular tumours and primary intraventricular haemorrhages. This test should therefore be given the same importance as spinal cord arteriography in the exploration of subarachnoid haemorrhages with negative cerebral angiograms.

Adolescent↗

[Spontaneous rhinorrhea due to (congenital?) evagination of arachnoidea in the paranasal sinuses].

Report on two cases of spontaneous, intermittent and long lasting spinal fluid rhinorrhea. The lesion responsible of the spinal fluid fistula is a glio-arachnoid expansion of the convexity of the frontal pole, contained into a fibrous pedicle ; it crosses the dura mater and penetrates, through a well individualized bone orifice, into the posterior wall of the frontal sinus or into an ethmoid-frontal cell. This arachnoid diverticle is not associated with an hydrocephalon. In the absence of any traumatic past history, its congenital nature may be admitted. No para-clinical investigation makes possible to detect such a minor abnormity ; the isotopic transit of the spinal fluid may remain silent, when performed at a moment of drying up of the nasal flow. Surgical exploratory study of the anterior level has to be complete, while numerous independent diverticles may coexist.

Adult↗