T lymphocyte dependence of the antibody response to 'T lymphocyte independent type 2' antigens.
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Biomedical subjects
Publications and source records attributed to A Jeurissen.
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Physical exercise has numerous effects on the human body, including the immune system. After strenuous exercise, athletes pass through a period of impaired immune resistance. During this period, athletes are theoretically more susceptible to upper respiratory tract infections, although a causal relation has never been demonstrated. Moderate exercise seems to have a beneficial effect on the immune function, which could protect against upper respiratory tract infections. Exercise has effects on both the humoral and the cellular immune system. Doping products, except glucocorticoids, only have modest effects on the immune system, although erythropoietin may, in rare cases, cause severe side-effects. Glutamine and vitamin C could, hypothetically, prevent the negative effects of strenuous exercise on the immune function, but further studies are needed to demonstrate and explain these effects.
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Antibody deficiency is the most common immunodeficiency. In 5% to 10% of the patients with recurrent infections that are evaluated for immunodeficiency, a specific deficiency in the immune response to capsular polysaccharides can be found. Patients with recurrent infections should therefore be tested for their capacity to produce antibodies against anti-capsular polysaccharides. As a clinical test, specific antibody levels are measured before and 14 days after immunization with the 23-valent pneumococcal polysaccharide vaccine. In this article we describe the indications, the method used to measure antibodies to capsular pneumococcal polysaccharide and the way the results have to be interpreted.
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