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Biomedical subjects

A Jus

Publications and source records attributed to A Jus.

At least 55 records · Page 3Linked to original sources
PubMed1968

Treatment of behaviour disorders in children with clinical and bioelectrical episodic symptomatology.

Fifty five children with episodic behaviour disorders and other behaviour disorders and a paroxysmal EEG pattern were examined clinically, psychologically and electroencephalographically. A detailed environmental analysis of social factors was made in each case. The aim of the study was a comparative analysis of the symptomatology and effects of treatment in behaviour disorders of children with and without an early lesion of the central nervous system. The authors have discussed the EEG-clinical correlations, the relationship between the effects of treatment and the clinical syndrome and EEG changes during treatment in the observed groups of children. The role of psychotherapy is emphasized, especially the influence of different environmental factors at home and at school.

Anticonvulsants↗
PubMedDate not supplied

A long-term study of penfluridol in chronic schizophrenia.

Penfluridol, a member of the novel diphenylbutylpiperidine class of antipsychotic drugs, is the first long-acting oral neuroleptic. The population of the present study consisted of 24 chronic schizophrenic patients (14 males, ten females) whose treatment with penfluridol was initiated in our previous open/double-blind trial lasting 32 weeks 1; mean age was 42.2 years and mean duration of illness, 15.4 years. During one additional year in an uncontrolled clinical study, penfluridol in the form of 20-mg capsuent procedures included BPRS, CGI, NOSIE, vital signs, and laboratory measurements. During this long-term treatment with penfluridol, the scores of a cluster of BPRS items that included emotional withdrawal, conceptual disorganization, motor retardation, uncooperativeness, and blunted affect showed a progressively significant improvement. This indicated that the Bleulerian primary symptoms in chronic schizophrenics can be improved by the long-term administration of this long-acting neuropleptic with concomitant betterment of social adaptation and activity. The percentage of failure was very low (four patients) and was marked by instability of psychopathology with periods of excitation. The incidence of extrapyramidal reactions necessitating the administration of an antiparkinsonian drug during the length of trial was 35 per cent. No serious effects nor significant laboratory test changes were observed.

Adult↗