Alpha-blockers decrease sympathetic influence and thus lower pressure in bladder neck region. Pharmacoprofilometry with tamsulosin was used in diagnostic dynamic outlet obstruction in 43 patients with benign prostatic hyperplasia (BPH) and in 17 patients with urethral stricture. 12 BPH patients with positive results of the test received tamsulosin in a single daily dose 0.4 mg. After 3 months the subjective symptom score significantly improved in all the patients. Stenosis of the urethra and bladder neck was found in 17 patients who had micturation disturbance in different periods after prostatectomy. In 9 patients urethral pressure in the region of the bladder neck decreased after 3 days of tamsulosin treatment given a single daily dose 0.4 mg. Urethrotomy without bladder neck resection was performed in these patients. Three months later average Q max increased from 6 ml/s to 18 ml/s and residual urine decreased from 112 ml to 30 ml. Selective alpha-blocker profilometry allows to distinguish between organic and functional neck stenosis and choose the necessary treatment.

Adrenergic alpha-Antagonists↗

PubMedDate not supplied

[Methods of studying and assessing the thromboresistance of polymeric materials].

Explore the source record for details and available documents.

In Vitro Techniques↗

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[Holmium laser treatment of benign prostatic hyperplasia].

Transurethral laser adenomectomy was performed in 37 patients with benign prostatic hyperplasia (BPH) aged 49-73 years (mean age 68 years) under epidural anesthesia. The intervention lasted 35-90 minutes (mean--55 minutes). Ho-YAG-laser was used (Versa Pulse, Coherent; 80 W, impulse regime, 2.09 microm, 50-100 Hz). 32 patients had intercurrent diseases (essential hypertension, diabetes mellitus, etc.). If the procedure technique was not violated, the postoperative period ran uneventfully. Coagulative effect of Ho-laser minimizes blood loss. Foley catheter was inserted. 12-24-h continuous irrigation of the urinary bladder was carried out. The drainage of the bladder with urethral catheter took 1-3 days. All the patients were discharged from hospital on postoperative day 5-7. Their condition was satisfactory. The patients were followed up for 8 months. Positive changes in urodynamics were recorded: I-PSS dropped from 21.4 to 11.2, maximal urine flow rate increased from 7.3 to 20.2 ml/s. Residual urine volume diminished to 0-30 ml compared to 190 ml before the operation. Secondary bleeding was absent. Minimal traumaticity and minimal blood loss allow to recommend laser adenomectomy both for BPH with and without intercurrent diseases.

Aged↗

PubMedDate not supplied

[Ho-YAG laser endoscopic treatment of ureteral strictures].

Ho-YAG-laser radiation with wave length 2.09 microns is a perspective line in high-energy laser treatment of urinary diseases. The authors have performed 24 operations in 23 patients with ureteral strictures. The antegrade approach was used in 11 patients while the retrograde one in 12 cases. Primary or secondary strictures occurred in 8 and 15 patients, respectively. Dissection and ablation of the scar tissues were conducted in 15 patients with secondary strictures. Cut of the stricture only was made in 8 patients with primary strictures. Ho-YAG-laser endoscopic treatment of secondary and primary ureteral strictures reached 93.3%(14 patients) and 75%(6 patients), respectively. Overall efficacy was 88.2%(20 patients). Ho-YAG-laser endopyeloplasty promoted quicker recovery of urodynamic and functional parameters of the upper urinary tract.

Adult↗

PubMedDate not supplied

[Acute urinary retention caused by urethral polyp].

A polyp of the prostatic part of the urethra is a rare pathological finding. A 20-year-old male visited our clinic with acute urinary retention. Ultrasound investigation, x-ray and endoscopic examinations revealed a polyp of the prostatic urethra. The polyp was resected by Ho-YAG laser. The resection resolved the urinary retention. The histopathological diagnosis was fibroepithelial polyp.

Acute Disease↗

PubMedDate not supplied

[Temporary ureteral stents in patients with neuorgenic dysfunction of the urinary bladder].

Biodegradable spiral stents were used in the treatment of detrusor external sphincter dyssynergia (4 patients) and detrusor areflexia with external sphincter spasticity (3 patients). All these patients had spinal injuries. After the stent placement all the patients could urinate almost without residual urine. In patients with detrusor-external sphincter dyssynergia mean voiding pressure was 79 cm water before treatment and 37 cm 10 weeks after the stent introduction. Biodegradable spiral stents are a promising treatment for patients with neurogenic bladder.

Adolescent↗