Sonographic in utero diagnosis of Klippel-Trenaunay-Weber syndrome.
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Biomedical subjects
Publications and source records attributed to A K Freimanis.
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We report on a syndrome of widow's peak, ptosis, skeletal abnormalities and other minor anomalies in a large family. The condition appears to be inherited in an X-linked dominant fashion. No similar cases have been found in the literature, suggesting that this is a "new" syndrome. Study of 5 generations of the family documents information on the natural history of the condition.
Magnetic resonance is a well-established imaging modality for CNS, but it's utility for visualizing the rest of the body has not been appreciated fully or exploited yet. The authors believe that MRI will become one of the primary imaging modalities for the body during the next several years. Current and future indications for magnetic resonance imaging of the body are discussed.
We have reviewed the radiologic imaging procedures related to the investigation of breast lesions, particularly carcinoma. We discussed the choice of procedure in certain clinical situations and have made suggestions. Of the imaging methods, x-ray mammography is the most useful. Ultrasound is the next most useful; however, it is not acceptable for screening. The basis for breast cancer detection and diagnosis remains palpation and x-ray mammography. Ultrasound makes a substantial contribution to the diagnostic evaluation of certain lesions. Eventually, biopsy or surgery provides the final answer in those patients with possible lesions after these diagnostic procedures. In view of the high incidence of breast carcinoma, it would be useful for the practitioner dealing with these problems to establish for his practice a standard operating procedure for examination and referral of patients for breast screening and diagnosis as well as a system of follow-up to prevent patients from avoiding the screening and diagnostic process.
We reviewed our experience with thyroid sonography of 60 patients with nonfunctioning (cold) solitary thyroid nodules proven by iodine 123 scan. Twenty-two patients had surgery; the remaining 38 had thyroid scan and ultrasound only. In the first group, the echograms did not demonstrate the surgically proven nodules in seven patients (32%). In the second group, the thyroid echograms were reported as negative in 12 patients (32%). Two of these patients had computerized tomography (CT) which confirmed the solitary nodule identified on the 123I scan. As a consequence, we no longer perform or recommend routine thyroid echograms on all scintigraphically cold solitary nodules. We believe that the extra cost of a thyroid echogram is not justified and that the most rational application of thyroid ultrasonography is in assessing the response of a nodule to suppressive hormonal therapy.
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The unique ability of ultrasound to detect soft tissue interfaces makes it a prime tool for at least one major diagnostic approach to soft tissue lesions. Systematic ultrasonic examination of suspected masses in the abdomen should be performed early in the course of investigation. It will help direct additional studies and often result in cost savings by making the diagnostic process more efficient. The method is painless, to the best of our knowledge harmless and can be repeated at will for early study or late follow-up. The ultrasonic look into the body has provided us with a major tool for obtaining far more information on internal structures than was possible even a few years ago. Ultrasonic scans, radioisotope examinations and computerized x-ray tomography are leading us into an era of much increased anatomic knowledge about lesions which heretofore were obscure and difficult to evaluate.
Reflected ultrasound scanning (echography) is rapidly developing into a prime tool for tumor diagnosis, outlining, and detection. The principles of echographic diagnosis of neoplasms, the accepted uses in detection and diagnosis, as well as some of the principles of internal and contour patterns are discussed. Echography is very helpful in determining the size, location, organ origin, internal characteristics, and course of neoplasms in the abdominal area, neck, and extremities. Echography is helpful in radiation therapy planning and is expected to assume an increasing role in the diagnosis and management of tumors.
For consistent identification of the normal pancreas, preliminary longitudinal scanning at, or near, the mid-line and subsequent oblique scanning in the long axis are necessary prerequisites in delineating the anatomic outline of the pancreas. The range of normal measurements for different anatomical regions of the pancreas was determined, based on the dimensional examinations of this organ in 328 patients free of pancreatic disease. These provide objective guidelines for analysis of the pancreas in abdominal echography. Echography provides a rapid, non-invasive method of imaging the pancreas. This study demonstrated that visualization of the pancreas as a separate structure does not imply that it is consequently abnormal.
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Movement of the diaphragm can be evaluated with diagnostic ultrasound using B- and M-mode techniques. Ultrasonic scanning is a highly sensitive method of demonstrating generalized or localized abnormalities of diaphragmatic motion and is superior to fluoroscopy in several respects. There is no exposure to ionizing radiations, and a permanent record of the excursion of the diaphragmatic surface is obtained. This method has the additional advantage of providing a two-dimensional display of the upper abdominal quadrant, which may reveal the nature of the underlying disease process.
The development of echographic diagnostic procedures for abdominal aortic aneurysms and enlarged abdominal lymph nodes has been discussed. The echographic method is suitable in several ways for the initial diagnosis, determination of extent, differential diagnosis, as well as follow-up of these abdominal lesions. The criteria for diagnosis and differential diagnosis have been presented and the advantages of the method and its limitations reviewed.
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