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Biomedical subjects

A K Goel

Publications and source records attributed to A K Goel.

At least 55 records · Page 3Linked to original sources
PubMed1985

Intravesical irrigation with alum for the control of massive bladder hemorrhage.

Continuous vesical irrigation with 1 per cent alum solution was performed without anesthesia in 9 patients in whom massive bladder hemorrhage persisted despite evacuation of clots and normal saline irrigation for at least 24 hours. Hematuria ceased promptly in all patients, although the effect was transient in 3. No side effect was observed. Biopsy of the tumor subsequent to alum irrigation showed no alteration in the histological characteristics. Biopsy of the normal-appearing bladder mucosa also showed no evidence of epithelial damage. Ultrastructure of the tumor in 1 patient in whom transurethral resection was performed 2 weeks after alum irrigation revealed well preserved nuclear chromatin, thus, suggesting that whatever changes occur after alum irrigation are short-lived.

Adult↗
PubMed1984

Non-operative management of extra-peritoneal rupture of the urinary bladder in a tetraplegic patient.

A 65-year-old male sustained a cervical spine injury and simultaneous extraperitoneal rupture of the urinary bladder. Because of co-existent severely impaired respiratory function the vesical rupture was managed conservatively and bladder drainage was provided by a 24 Fr. indwelling urethral catheter. Serial cystograms performed at 4, 7 and 9 weeks post-injury showed complete healing by 63 days. We suggest that non-operative management of vesical rupture should be considered in selected patients with associated serious other body system involvement.

Aged↗
PubMedDate not supplied

Implantable cardioverter defibrillator therapy in children with long QT syndrome.

We report our experience with implantable cardioverter defibrillator (ICD) implantation and follow-up in high-risk patients with congenital long QT syndrome (LQTS). Congenital LQTS is associated with significant risk of malignant ventricular arrhythmias and sudden cardiac death (SCD). ICD implant is recommended for prevention of SCD in this patient population, but there are few published data regarding the efficacy and side effects of such therapy. We report our experience with 12 patients who underwent ICD implant for high-risk LQTS at our center in the past 5 years with respect to implant complications, appropriate and inappropriate therapies, device follow-up, and the impact on lifestyle. During a follow-up of 34.7+/-16.6 months, appropriate therapies were noted in 5, inappropriate therapies in 4, and no therapies in 3 patients. Clusters of appropriate therapies were seen in 3 patients, 1 of whom subsequently died. Female sex and congenital deafness appear to be associated with a higher risk of appropriate therapies. One patient experienced two complications at implant that were successfully treated. ICD implantation in LQTS patients presenting with SCD or recurrent syncope despite beta-blocker therapy appears to be justified in preventing SCD risk. In asymptomatic siblings of SCD patients, the benefits of ICD implant are not clear from our data.

Adolescent↗
PubMedDate not supplied

Atrioventricular septal defect with cor triatriatum: case report and review of the literature.

Atrioventricular septal defect with cor triatriatum is a rare combination, with only nine cases reported so far. Cor triatriatum, a potentially correctable cause of pulmonary arterial hypertension in atrioventricular septal defect patients, was missed in a few earlier case reports, leading to death and subsequent diagnosis at autopsy. We report the case of 3-year-old female child with this combination (partial atrioventricular septal defect with cor triatriatum) wherein the final diagnosis was made at cardiac catheterization. Successful surgical correction was performed.

Abnormalities, Multiple↗
PubMedDate not supplied

Transesophageal echocardiography in the presence of left atrial calcification.

Calcification of left atrial walls is a rare finding that has been reported to hamper visibility of intracardiac structures during transesophageal echocardiography because of the posterior location of the left atrium. We report a case of severe mitral stenosis associated with heavy left atrial calcification in which we could obtain good quality transesophageal imaging in spite of such a calcification. We conclude that calcification of left atrial walls does not necessarily imply a limitation of transesophageal echocardiography.

Adolescent↗
PubMedDate not supplied

Transesophageal echocardiography during surgical closed mitral commissurotomy.

We report a case of a 28-year-old woman with severe mitral stenosis for which surgical closed commissurotomy was done. Intraoperative transesophageal echocardiography was performed to assess its utility during this surgical procedure. It was helpful in instant confirmation of the adequacy of the surgery, detecting residual mitral regurgitation, and in visualisation of the Tubbs dilator that is used to accomplish mitral commissurotomy.

Adult↗
PubMedDate not supplied

Circadian desynchronization in pulse rate, systolic and diastolic blood pressure, rectal temperature and urine output in traumatic tetraplegics.

An investigation was undertaken to study the circadian rhythmicity in pulse rate, systolic and diastolic blood pressure, rectal temperature and urine output in eight traumatic tetraplegics in view of the fact that diurnal rhythmicity in prolactin response to thyrotropin-releasing hormone was absent in such patients. The data, analysed by single cosinor procedure, showed absence of rhythmicity in all five parameters. Analysis of variance also showed no significant difference in these parameters at various time points. Knowledge of the alterations in circadian biology subsequent to cervical spinal cord trauma would provide useful guidelines towards chronotherapy and vocational rehabilitation of tetraplegics besides possible restoration of euchronism by pharmacological means.

Adolescent↗